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- W1990355539 abstract "British Journal of HaematologyVolume 77, Issue 3 p. 440-441 Free Access ASSESSMENT OF ORAL 1,2-DIMETHYL–3-HYDROXYPYRID–4–ONE (L1) IN DIFFERENT FERRIKINETIC MODELS IN ANIMALS AND HUMANS G. J. Kontoghiorghes, G. J. Kontoghiorghes Department of Haematology, Royal Free Hospital and School of Medicine, London NW3 2QGSearch for more papers by this author G. J. Kontoghiorghes, G. J. Kontoghiorghes Department of Haematology, Royal Free Hospital and School of Medicine, London NW3 2QGSearch for more papers by this author First published: March 1991 https://doi.org/10.1111/j.1365-2141.1991.tb08601.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. References Klaasen, C.D. & Watkins, J.B. (1984) Mechanism of bile formation, hepatic uptake and biliary excretion. Pharmacology Reviews, 36, 1– 67. Kontoghiorghes, G.J. (1986) Orally active α-ketohydroxypyridine iron chelators: studies in mice. Molecular Pharmacology, 30, 670– 673. Kontoghiorghes, G.J., Chambers, S., Dodd, A. & Thompson, H. (1986) In vivo ferrokinetic studies and the site of action of chelators. British Journal of Haematology, 64, 839– 840. Kontoghiorghes, G.J., Sheppard, L., Hoffbrand, A.V., Charalambus, J., Tikerpae, J. & Pippard, M.J. (1987) Iron chelation studies using desferrioxamine and the potential oral chelator 1,2-dimethyl–3-hydroxypyrid–4-one, in normal and iron overloaded rats. Journal of Clinical Pathology, 40, 404– 408. Kontoghiorghes, C.J., Bartlett, A.N., Hoffbrand, A.V., Goddard, J.C., Sheppard, L., Barr, J. & Nortey, P. (1990a) Long term trial with the oral iron chelator 1,2-dimethyl–3-hydroxypyrid–4-one (L1). (I) Iron chelation and metabolic studies. British Journal of Haematology, 76, 295– 300. Kontoghiorghes, C.J., Goddard, J.G., Bartlett, A.N. & Sheppard, L. (1990b) Pharmacokinetic studies in man with the oral iron chelator 1,2-dimethyl–3-hydroxypyrid–4-one. Clinical Pharmacology and Therapeutics, 48, 255– 261. Venkataram, S. & Rahman, Y.E. (1990) Studies of an oral iron chelator: 1,2-dimethyl–3-hydroxypyrid–4-one. I. Iron excretion in rats: development of a new rapid microwave method for iron analysis in faeces. British Journal of Haematology, 75, 274– 277. Citing Literature Volume77, Issue3March 1991Pages 440-441 ReferencesRelatedInformation" @default.
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