Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990363090> ?p ?o ?g. }
- W1990363090 endingPage "3628" @default.
- W1990363090 startingPage "3619" @default.
- W1990363090 abstract "Cell-cell fusion in animal development and in pathophysiology involves expansion of nascent fusion pores formed by protein fusogens to yield an open lumen of cell-size diameter. Here we explored the enlargement of micron-scale pores in syncytium formation, which was initiated by a well-characterized fusogen baculovirus gp64. Radial expansion of a single or, more often, of multiple fusion pores proceeds without loss of membrane material in the tight contact zone. Pore growth requires cell metabolism and is accompanied by a local disassembly of the actin cortex under the pores. Effects of actin-modifying agents indicate that the actin cortex slows down pore expansion. We propose that the growth of the strongly bent fusion-pore rim is restricted by a dynamic resistance of the actin network and driven by membrane-bending proteins that are involved in the generation of highly curved intracellular membrane compartments." @default.
- W1990363090 created "2016-06-24" @default.
- W1990363090 creator A5013396870 @default.
- W1990363090 creator A5042083317 @default.
- W1990363090 creator A5050732065 @default.
- W1990363090 creator A5062465955 @default.
- W1990363090 creator A5072189090 @default.
- W1990363090 creator A5081800011 @default.
- W1990363090 date "2008-11-01" @default.
- W1990363090 modified "2023-09-23" @default.
- W1990363090 title "Fusion-pore expansion during syncytium formation is restricted by an actin network" @default.
- W1990363090 cites W1485384468 @default.
- W1990363090 cites W1490759475 @default.
- W1990363090 cites W1536475774 @default.
- W1990363090 cites W1546065744 @default.
- W1990363090 cites W1597391547 @default.
- W1990363090 cites W1821635550 @default.
- W1990363090 cites W1840209374 @default.
- W1990363090 cites W1866340627 @default.
- W1990363090 cites W1967036697 @default.
- W1990363090 cites W1968639886 @default.
- W1990363090 cites W1973393856 @default.
- W1990363090 cites W1973642611 @default.
- W1990363090 cites W1980755477 @default.
- W1990363090 cites W1986572128 @default.
- W1990363090 cites W1988257424 @default.
- W1990363090 cites W1988762133 @default.
- W1990363090 cites W1990380758 @default.
- W1990363090 cites W1990917234 @default.
- W1990363090 cites W1991447699 @default.
- W1990363090 cites W1992233783 @default.
- W1990363090 cites W1992425845 @default.
- W1990363090 cites W1996983058 @default.
- W1990363090 cites W2007483105 @default.
- W1990363090 cites W2012107438 @default.
- W1990363090 cites W2015454830 @default.
- W1990363090 cites W2015611396 @default.
- W1990363090 cites W2017988722 @default.
- W1990363090 cites W2028746635 @default.
- W1990363090 cites W2041703789 @default.
- W1990363090 cites W2046535546 @default.
- W1990363090 cites W2053927358 @default.
- W1990363090 cites W2056657105 @default.
- W1990363090 cites W2067217032 @default.
- W1990363090 cites W2069633295 @default.
- W1990363090 cites W2072167784 @default.
- W1990363090 cites W2073090407 @default.
- W1990363090 cites W2073561449 @default.
- W1990363090 cites W2074270575 @default.
- W1990363090 cites W2076971529 @default.
- W1990363090 cites W2080795990 @default.
- W1990363090 cites W2084174084 @default.
- W1990363090 cites W2084636380 @default.
- W1990363090 cites W2084707381 @default.
- W1990363090 cites W2087564308 @default.
- W1990363090 cites W2091001172 @default.
- W1990363090 cites W2093236242 @default.
- W1990363090 cites W2097794398 @default.
- W1990363090 cites W2105384628 @default.
- W1990363090 cites W2105630800 @default.
- W1990363090 cites W2108071074 @default.
- W1990363090 cites W2108472247 @default.
- W1990363090 cites W2109459280 @default.
- W1990363090 cites W2115657143 @default.
- W1990363090 cites W2116519871 @default.
- W1990363090 cites W2121496544 @default.
- W1990363090 cites W2122201690 @default.
- W1990363090 cites W2123151328 @default.
- W1990363090 cites W2125562692 @default.
- W1990363090 cites W2127939214 @default.
- W1990363090 cites W2133958949 @default.
- W1990363090 cites W2135334901 @default.
- W1990363090 cites W2140228548 @default.
- W1990363090 cites W2148474745 @default.
- W1990363090 cites W2153668165 @default.
- W1990363090 cites W2158516223 @default.
- W1990363090 cites W2161094378 @default.
- W1990363090 cites W2167848031 @default.
- W1990363090 cites W2168174819 @default.
- W1990363090 cites W2169274584 @default.
- W1990363090 cites W2169338512 @default.
- W1990363090 cites W2169621308 @default.
- W1990363090 cites W2411831848 @default.
- W1990363090 cites W2414495012 @default.
- W1990363090 cites W2416848561 @default.
- W1990363090 cites W4210958643 @default.
- W1990363090 doi "https://doi.org/10.1242/jcs.032169" @default.
- W1990363090 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3552434" @default.
- W1990363090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18946025" @default.
- W1990363090 hasPublicationYear "2008" @default.
- W1990363090 type Work @default.
- W1990363090 sameAs 1990363090 @default.
- W1990363090 citedByCount "46" @default.
- W1990363090 countsByYear W19903630902012 @default.
- W1990363090 countsByYear W19903630902013 @default.
- W1990363090 countsByYear W19903630902014 @default.
- W1990363090 countsByYear W19903630902015 @default.
- W1990363090 countsByYear W19903630902016 @default.