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- W1990367261 abstract "La tuberculose congénitale est rare mais sévère. Le retard diagnostique classiquement retrouvé peut être aggravé par le contexte de la prématurité. Nous rapportons le cas d’un nouveau-né prématuré de 27 semaines d’aménorrhée, né d’une grossesse obtenue par fécondation in vitro pour infertilité de 13 ans. Le diagnostic a été suspecté après 112j de vie devant un tableau de sepsis et de détresse respiratoire récidivante, et la découverte d’une tuberculose maternelle. Mycobacterium tuberculosis a été trouvé dans les selles, les tubages gastriques et les crachats. L’enfant a reçu avec succès une quadri-antibiothérapie pendant 3 mois, puis une bi-antibiothérapie pendant neuf mois. Un dépistage large d’une éventuelle transmission nosocomiale à partir de cet enfant a été mis en place. À l’âge de 2 ans, l’enfant se portait bien. Aucun cas secondaire n’a été diagnostiqué. Ce cas rappelle la difficulté du diagnostic de tuberculose congénitale, en particulier dans le contexte de la grande prématurité. Il souligne également la nécessité de rechercher le diagnostic de tuberculose dans le bilan d’infertilité. Congenital tuberculosis is a rare but severe disease. Diagnosis is often delayed, especially in preterm neonates. We report a premature infant born after 27 weeks of gestation and in vitro fertilization. Tuberculosis was suspected after 112 days of life in view of sepsis, respiratory distress, and the discovery of maternal tuberculosis. Mycobacterium tuberculosis was isolated in endotracheal aspirates, gastric aspirates, and stools. The infant initially received four antitubercular antibiotics over 3 months, then two antibiotics over 9 months. A wide screening for a possible nosocomial transmission from this index case was set up. At the chronological age of 2 years, the baby is healthy without after-effects and no secondary cases were diagnosed. This article recalls the difficulty diagnosing congenital tuberculosis, particularly in preterm neonates. It also underlines the need to raise and eliminate the diagnosis of tuberculosis in an infertile woman." @default.
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- W1990367261 date "2009-05-01" @default.
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- W1990367261 title "Tuberculose congénitale chez le nouveau-né prématuré : à propos d’un cas" @default.
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- W1990367261 doi "https://doi.org/10.1016/j.arcped.2009.02.003" @default.
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