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- W1990372900 abstract "In our continuing effort to discover more new cytotoxic sesquiterpenoid from Solanum lyratum collected from different districts of China, three new sesquiterpenoids, attributable to eudesmane-type (1, named solajiangxin D) and vetispirane-type (2–3, named solajiangxins E and 2-hydroxysolajiangxin E), respectively, were isolated. Their structures were elucidated on the basis of integrated spectroscopic techniques, mainly HR-FABMS, 1D and 2D NMR (1H–1H COSY, HMQC, HMBC and ROESY). In vitro, compounds 1–3 were found to show significant cytotoxicities against three human cancer lines (P-388, HONE-1, and HT-29), and gave ED50 values in the range 2.1–3.7 μg/ml." @default.
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- W1990372900 date "2013-08-01" @default.
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- W1990372900 title "Three new cytotoxic sesquiterpenoids from Solanum lyratum" @default.
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- W1990372900 doi "https://doi.org/10.1016/j.phytol.2013.05.012" @default.
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