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- W1990392023 abstract "<h2>Abstract</h2> CHIP acts as a hypoxic cell sensitizer when used in conjunction with X-irradiation. A change in the extrapolation number of the radiation survival curve of chinese hamster ovary (CHO) cells is observed but the exponential slope (D<sub>0</sub>) remains the same. Chinese hamster ovary cells appear to be less sensitive than C<sub>3</sub>H mouse mammary tumor cells to CHIP. The type and level of chromosome aberrations observed in CHO cells indicate that the mechanism of action of CHIP is similar to that seen with bifunctional alkylating agents." @default.
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- W1990392023 date "1979-08-01" @default.
- W1990392023 modified "2023-10-17" @default.
- W1990392023 title "The mechanism of action of cis-dichloro-bis (isopropylamine) trans dihydroxyplatinum IV (CHIP) on Chinese hamster and C3H mouse tumor cells and its interaction with X-irradiation" @default.
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- W1990392023 doi "https://doi.org/10.1016/0360-3016(79)90666-7" @default.
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