FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990398013> ?p ?o ?g. }

• W1990398013 endingPage "1033" @default.
• W1990398013 startingPage "1025" @default.
• W1990398013 abstract "Prophylactic hyperventilation of patients with head injuries worsens outcome, presumably by exacerbating tissue hypoxia. Oxygen tension in brain tissue (PbrO2) provides a direct measurement of cerebral metabolic substrate delivery and varies with changing end-tidal carbon dioxide tension (ETCO2) and mean arterial pressure. However, the effects of hyperventilation and hypoventilation on PbrO2 during hemorrhagic shock are not known. The aim of this study was to examine the effects of alteration in ventilation on PbrO2 in hemorrhaged swine.Clark-type polarographic probes were inserted into the brain tissue of seven swine to measure PbrO2 directly. To examine the effects of alterations in ventilation on hemorrhage-induced hypotension, swine were hemorrhaged to 50% estimated blood volume and PbrO2 was monitored during hyperventilation (RR = 30) and hypoventilation (RR = 4).After the 50% hemorrhage, PbrO2 declined rapidly from 39.8 +/- 4.6 mm Hg to 11.4 +/- 2.2 mm Hg. Hyperventilation resulted in a further 56% mean decrease in PbrO2. Hypoventilation produced a 166% mean increase in PbrO2. These changes were significant (p = 0.001) for absolute and percentage differences from baseline.During hemorrhage, alterations in ventilation significantly changed PbrO2: hyperventilation increased brain-tissue hypoxia whereas hypoventilation alleviated it. This finding suggests that hyperventilation has deleterious effects on brain oxygenation in patients with hemorrhagic shock and those with head trauma. Conversely, hypoventilation with resultant hypercapnia may actually help resolve hemorrhagic shock-induced cerebral hypoxia." @default.
• W1990398013 created "2016-06-24" @default.
• W1990398013 creator A5010173440 @default.
• W1990398013 creator A5020219734 @default.
• W1990398013 creator A5033880040 @default.
• W1990398013 creator A5034085788 @default.
• W1990398013 creator A5040370380 @default.
• W1990398013 creator A5041719015 @default.
• W1990398013 creator A5081110323 @default.
• W1990398013 date "2000-06-01" @default.
• W1990398013 modified "2023-10-14" @default.
• W1990398013 title "Cerebral Oxygenation during Hemorrhagic Shock: Perils of Hyperventilation and the Therapeutic Potential of Hypoventilation" @default.
• W1990398013 cites W1985939052 @default.
• W1990398013 cites W2023388756 @default.
• W1990398013 cites W2028299889 @default.
• W1990398013 cites W2047100038 @default.
• W1990398013 cites W2059058279 @default.
• W1990398013 cites W2080587512 @default.
• W1990398013 cites W2150833402 @default.
• W1990398013 cites W2152626368 @default.
• W1990398013 cites W2162892324 @default.
• W1990398013 cites W2173135046 @default.
• W1990398013 cites W2291672255 @default.
• W1990398013 cites W2334883237 @default.
• W1990398013 cites W2351394024 @default.
• W1990398013 cites W4232788895 @default.
• W1990398013 doi "https://doi.org/10.1097/00005373-200006000-00005" @default.
• W1990398013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10866246" @default.
• W1990398013 hasPublicationYear "2000" @default.
• W1990398013 type Work @default.
• W1990398013 sameAs 1990398013 @default.
• W1990398013 citedByCount "79" @default.
• W1990398013 countsByYear W19903980132012 @default.
• W1990398013 countsByYear W19903980132013 @default.
• W1990398013 countsByYear W19903980132014 @default.
• W1990398013 countsByYear W19903980132015 @default.
• W1990398013 countsByYear W19903980132016 @default.
• W1990398013 countsByYear W19903980132017 @default.
• W1990398013 countsByYear W19903980132019 @default.
• W1990398013 countsByYear W19903980132020 @default.
• W1990398013 countsByYear W19903980132021 @default.
• W1990398013 crossrefType "journal-article" @default.
• W1990398013 hasAuthorship W1990398013A5010173440 @default.
• W1990398013 hasAuthorship W1990398013A5020219734 @default.
• W1990398013 hasAuthorship W1990398013A5033880040 @default.
• W1990398013 hasAuthorship W1990398013A5034085788 @default.
• W1990398013 hasAuthorship W1990398013A5040370380 @default.
• W1990398013 hasAuthorship W1990398013A5041719015 @default.
• W1990398013 hasAuthorship W1990398013A5081110323 @default.
• W1990398013 hasConcept C126322002 @default.
• W1990398013 hasConcept C127413603 @default.
• W1990398013 hasConcept C178790620 @default.
• W1990398013 hasConcept C185592680 @default.
• W1990398013 hasConcept C200457457 @default.
• W1990398013 hasConcept C2777037550 @default.
• W1990398013 hasConcept C2777140959 @default.
• W1990398013 hasConcept C2777449187 @default.
• W1990398013 hasConcept C2778553927 @default.
• W1990398013 hasConcept C2778866228 @default.
• W1990398013 hasConcept C2779594553 @default.
• W1990398013 hasConcept C2781300812 @default.
• W1990398013 hasConcept C2993207723 @default.
• W1990398013 hasConcept C42219234 @default.
• W1990398013 hasConcept C534529494 @default.
• W1990398013 hasConcept C540031477 @default.
• W1990398013 hasConcept C70289976 @default.
• W1990398013 hasConcept C71924100 @default.
• W1990398013 hasConcept C7836513 @default.
• W1990398013 hasConcept C78519656 @default.
• W1990398013 hasConcept C79959777 @default.
• W1990398013 hasConceptScore W1990398013C126322002 @default.
• W1990398013 hasConceptScore W1990398013C127413603 @default.
• W1990398013 hasConceptScore W1990398013C178790620 @default.
• W1990398013 hasConceptScore W1990398013C185592680 @default.
• W1990398013 hasConceptScore W1990398013C200457457 @default.
• W1990398013 hasConceptScore W1990398013C2777037550 @default.
• W1990398013 hasConceptScore W1990398013C2777140959 @default.
• W1990398013 hasConceptScore W1990398013C2777449187 @default.
• W1990398013 hasConceptScore W1990398013C2778553927 @default.
• W1990398013 hasConceptScore W1990398013C2778866228 @default.
• W1990398013 hasConceptScore W1990398013C2779594553 @default.
• W1990398013 hasConceptScore W1990398013C2781300812 @default.
• W1990398013 hasConceptScore W1990398013C2993207723 @default.
• W1990398013 hasConceptScore W1990398013C42219234 @default.
• W1990398013 hasConceptScore W1990398013C534529494 @default.
• W1990398013 hasConceptScore W1990398013C540031477 @default.
• W1990398013 hasConceptScore W1990398013C70289976 @default.
• W1990398013 hasConceptScore W1990398013C71924100 @default.
• W1990398013 hasConceptScore W1990398013C7836513 @default.
• W1990398013 hasConceptScore W1990398013C78519656 @default.
• W1990398013 hasConceptScore W1990398013C79959777 @default.
• W1990398013 hasIssue "6" @default.
• W1990398013 hasLocation W19903980131 @default.
• W1990398013 hasLocation W19903980132 @default.
• W1990398013 hasOpenAccess W1990398013 @default.
• W1990398013 hasPrimaryLocation W19903980131 @default.
• W1990398013 hasRelatedWork W169824024 @default.
• W1990398013 hasRelatedWork W1974735213 @default.

• next