Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990407142> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1990407142 endingPage "114" @default.
- W1990407142 startingPage "105" @default.
- W1990407142 abstract "A recently proposed approach for the study of the intercalation equilibria of drugs and polynucleotides is applied to ethidium bromide and poly(inosinic)–poly(cytidylic) acid. The procedure consists of the extension of the continuous variation and mole-ratio methods by recording all the UV–VIS absorption, fluorescence and circular dichroism spectra for a set of solutions containing a range of polynucleotide:dye concentration ratios. The whole set of spectroscopic data matrices was simultaneously analyzed by a multivariate curve resolution method based on alternating least squares. This procedure allowed the detection of the intercalation complex, the recovery of the concentration profiles and pure spectra for each species and the calculation of the polynucleotide:dye ratio in the complex and the apparent equilibrium constant. The intercalation sites occur every three base pairs and the value for the logarithm of the apparent equilibrium constant at 37°C in 0.26 M NaCl was 4.6±0.1 M−1." @default.
- W1990407142 created "2016-06-24" @default.
- W1990407142 creator A5001144697 @default.
- W1990407142 creator A5026458876 @default.
- W1990407142 creator A5040371776 @default.
- W1990407142 date "2000-11-01" @default.
- W1990407142 modified "2023-10-16" @default.
- W1990407142 title "Multivariate extension of the continuous variation and mole-ratio methods for the study of the interaction of intercalators with polynucleotides" @default.
- W1990407142 cites W1982007541 @default.
- W1990407142 cites W1988365919 @default.
- W1990407142 cites W1993419109 @default.
- W1990407142 cites W1994000836 @default.
- W1990407142 cites W1994015185 @default.
- W1990407142 cites W2001191453 @default.
- W1990407142 cites W200778230 @default.
- W1990407142 cites W2021648652 @default.
- W1990407142 cites W2023630025 @default.
- W1990407142 cites W2026039391 @default.
- W1990407142 cites W2026767654 @default.
- W1990407142 cites W2030823944 @default.
- W1990407142 cites W2059852996 @default.
- W1990407142 cites W2064092455 @default.
- W1990407142 cites W2069753895 @default.
- W1990407142 cites W2077396245 @default.
- W1990407142 cites W2082505332 @default.
- W1990407142 cites W2117575839 @default.
- W1990407142 cites W2117716727 @default.
- W1990407142 cites W2146226340 @default.
- W1990407142 cites W2150586056 @default.
- W1990407142 cites W2410004250 @default.
- W1990407142 doi "https://doi.org/10.1016/s0003-2670(00)01029-1" @default.
- W1990407142 hasPublicationYear "2000" @default.
- W1990407142 type Work @default.
- W1990407142 sameAs 1990407142 @default.
- W1990407142 citedByCount "46" @default.
- W1990407142 countsByYear W19904071422012 @default.
- W1990407142 countsByYear W19904071422013 @default.
- W1990407142 countsByYear W19904071422014 @default.
- W1990407142 countsByYear W19904071422015 @default.
- W1990407142 countsByYear W19904071422016 @default.
- W1990407142 countsByYear W19904071422017 @default.
- W1990407142 countsByYear W19904071422019 @default.
- W1990407142 countsByYear W19904071422021 @default.
- W1990407142 crossrefType "journal-article" @default.
- W1990407142 hasAuthorship W1990407142A5001144697 @default.
- W1990407142 hasAuthorship W1990407142A5026458876 @default.
- W1990407142 hasAuthorship W1990407142A5040371776 @default.
- W1990407142 hasConcept C10710636 @default.
- W1990407142 hasConcept C111921641 @default.
- W1990407142 hasConcept C113196181 @default.
- W1990407142 hasConcept C137824038 @default.
- W1990407142 hasConcept C147789679 @default.
- W1990407142 hasConcept C179104552 @default.
- W1990407142 hasConcept C185592680 @default.
- W1990407142 hasConcept C2776907736 @default.
- W1990407142 hasConcept C43617362 @default.
- W1990407142 hasConcept C552990157 @default.
- W1990407142 hasConcept C55493867 @default.
- W1990407142 hasConceptScore W1990407142C10710636 @default.
- W1990407142 hasConceptScore W1990407142C111921641 @default.
- W1990407142 hasConceptScore W1990407142C113196181 @default.
- W1990407142 hasConceptScore W1990407142C137824038 @default.
- W1990407142 hasConceptScore W1990407142C147789679 @default.
- W1990407142 hasConceptScore W1990407142C179104552 @default.
- W1990407142 hasConceptScore W1990407142C185592680 @default.
- W1990407142 hasConceptScore W1990407142C2776907736 @default.
- W1990407142 hasConceptScore W1990407142C43617362 @default.
- W1990407142 hasConceptScore W1990407142C552990157 @default.
- W1990407142 hasConceptScore W1990407142C55493867 @default.
- W1990407142 hasIssue "1" @default.
- W1990407142 hasLocation W19904071421 @default.
- W1990407142 hasOpenAccess W1990407142 @default.
- W1990407142 hasPrimaryLocation W19904071421 @default.
- W1990407142 hasRelatedWork W185039587 @default.
- W1990407142 hasRelatedWork W2004577306 @default.
- W1990407142 hasRelatedWork W2030823944 @default.
- W1990407142 hasRelatedWork W2035670306 @default.
- W1990407142 hasRelatedWork W2341131457 @default.
- W1990407142 hasRelatedWork W2396656261 @default.
- W1990407142 hasRelatedWork W2404156384 @default.
- W1990407142 hasRelatedWork W2415482420 @default.
- W1990407142 hasRelatedWork W3053010731 @default.
- W1990407142 hasRelatedWork W4319999318 @default.
- W1990407142 hasVolume "424" @default.
- W1990407142 isParatext "false" @default.
- W1990407142 isRetracted "false" @default.
- W1990407142 magId "1990407142" @default.
- W1990407142 workType "article" @default.