FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990433946> ?p ?o ?g. }

• W1990433946 endingPage "419" @default.
• W1990433946 startingPage "413" @default.
• W1990433946 abstract "Objective. Bikunin is an inhibitor of kidney stone formation synthesized in the liver together with α1-microglobulin from the α1-microglobulin/bikunin precursor (AMBP) gene. The aim of this study was to investigate the possible association between bikunin/AMBP gene polymorphisms and urinary stone formation. Material and methods. To analyse the DNA, blood samples were taken from 75 kidney stone formers who had a familial stone history, 35 sporadic stone formers and 101 healthy individuals. Four exons of bikunin gene and five parts of the promoter region of the AMBP gene were screened using single-strand conformation polymorphism and nucleotide sequence analysis. Results. The Init-2 region of the promoter of AMBP gene had polymorphisms at positions -218 and -189 nt giving three different genotypes having 1,3, 2,4 and 1,2,3,4 alleles with frequencies of 17.06%, 60.19% and 22.75%, respectively, in all groups. Therefore, the Init-2 region appears to be polymorphic. As a result, the 1,3 allele has -218G and -189T complying with the reference database sequence, the 2,4 allele has -218G and T-189C substitution and the allele 1,2,3,4 genotype has substitutions at positions G-218C and T-189C. Conclusions. There were no significant differences in allele distribution between patients and controls. These common alleles exist in the Turkish population independent of stone formation. These results are the first to demonstrate the existence of bikunin and AMBP promoter polymorphism. Although the Init-2 region of the AMBP gene is the binding site for various transcription factors, the results showed no association between these observed genotypes and stone-forming phenotypes." @default.
• W1990433946 created "2016-06-24" @default.
• W1990433946 creator A5000034749 @default.
• W1990433946 creator A5006568209 @default.
• W1990433946 creator A5040876711 @default.
• W1990433946 creator A5046597932 @default.
• W1990433946 creator A5060026181 @default.
• W1990433946 creator A5068699848 @default.
• W1990433946 creator A5082745110 @default.
• W1990433946 creator A5085355713 @default.
• W1990433946 creator A5089533331 @default.
• W1990433946 date "2010-07-05" @default.
• W1990433946 modified "2023-10-17" @default.
• W1990433946 title "Bikunin and α1-microglobulin/bikunin precursor (AMBP) gene mutational screening in patients with kidney stones: A case-control study" @default.
• W1990433946 cites W1514189471 @default.
• W1990433946 cites W1532306565 @default.
• W1990433946 cites W1602700702 @default.
• W1990433946 cites W1820585906 @default.
• W1990433946 cites W1966098888 @default.
• W1990433946 cites W1966390662 @default.
• W1990433946 cites W1978374861 @default.
• W1990433946 cites W1984911288 @default.
• W1990433946 cites W1994726563 @default.
• W1990433946 cites W1995684702 @default.
• W1990433946 cites W1998416472 @default.
• W1990433946 cites W2003379513 @default.
• W1990433946 cites W2010457940 @default.
• W1990433946 cites W2010676786 @default.
• W1990433946 cites W2020309536 @default.
• W1990433946 cites W2020973522 @default.
• W1990433946 cites W2021879369 @default.
• W1990433946 cites W2025631745 @default.
• W1990433946 cites W2028715927 @default.
• W1990433946 cites W2036275864 @default.
• W1990433946 cites W2036759807 @default.
• W1990433946 cites W2046486509 @default.
• W1990433946 cites W2048487517 @default.
• W1990433946 cites W2060921373 @default.
• W1990433946 cites W2066709989 @default.
• W1990433946 cites W2067517862 @default.
• W1990433946 cites W2068284848 @default.
• W1990433946 cites W2071529815 @default.
• W1990433946 cites W2073201075 @default.
• W1990433946 cites W2074516286 @default.
• W1990433946 cites W2076389686 @default.
• W1990433946 cites W2087576610 @default.
• W1990433946 cites W2108135980 @default.
• W1990433946 cites W2114897687 @default.
• W1990433946 cites W2123627169 @default.
• W1990433946 cites W2127910592 @default.
• W1990433946 cites W2131055961 @default.
• W1990433946 cites W2133831451 @default.
• W1990433946 cites W2135332883 @default.
• W1990433946 cites W2139640966 @default.
• W1990433946 cites W2165934077 @default.
• W1990433946 cites W2170085040 @default.
• W1990433946 cites W2327781251 @default.
• W1990433946 cites W4210978414 @default.
• W1990433946 doi "https://doi.org/10.3109/00365599.2010.497768" @default.
• W1990433946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20602574" @default.
• W1990433946 hasPublicationYear "2010" @default.
• W1990433946 type Work @default.
• W1990433946 sameAs 1990433946 @default.
• W1990433946 citedByCount "4" @default.
• W1990433946 countsByYear W19904339462014 @default.
• W1990433946 countsByYear W19904339462016 @default.
• W1990433946 crossrefType "journal-article" @default.
• W1990433946 hasAuthorship W1990433946A5000034749 @default.
• W1990433946 hasAuthorship W1990433946A5006568209 @default.
• W1990433946 hasAuthorship W1990433946A5040876711 @default.
• W1990433946 hasAuthorship W1990433946A5046597932 @default.
• W1990433946 hasAuthorship W1990433946A5060026181 @default.
• W1990433946 hasAuthorship W1990433946A5068699848 @default.
• W1990433946 hasAuthorship W1990433946A5082745110 @default.
• W1990433946 hasAuthorship W1990433946A5085355713 @default.
• W1990433946 hasAuthorship W1990433946A5089533331 @default.
• W1990433946 hasConcept C101762097 @default.
• W1990433946 hasConcept C104317684 @default.
• W1990433946 hasConcept C129219603 @default.
• W1990433946 hasConcept C135763542 @default.
• W1990433946 hasConcept C150194340 @default.
• W1990433946 hasConcept C153911025 @default.
• W1990433946 hasConcept C180754005 @default.
• W1990433946 hasConcept C2908647359 @default.
• W1990433946 hasConcept C36823959 @default.
• W1990433946 hasConcept C54355233 @default.
• W1990433946 hasConcept C71924100 @default.
• W1990433946 hasConcept C86803240 @default.
• W1990433946 hasConcept C99454951 @default.
• W1990433946 hasConceptScore W1990433946C101762097 @default.
• W1990433946 hasConceptScore W1990433946C104317684 @default.
• W1990433946 hasConceptScore W1990433946C129219603 @default.
• W1990433946 hasConceptScore W1990433946C135763542 @default.
• W1990433946 hasConceptScore W1990433946C150194340 @default.
• W1990433946 hasConceptScore W1990433946C153911025 @default.
• W1990433946 hasConceptScore W1990433946C180754005 @default.
• W1990433946 hasConceptScore W1990433946C2908647359 @default.
• W1990433946 hasConceptScore W1990433946C36823959 @default.

• next