FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990436170> ?p ?o ?g. }

• W1990436170 endingPage "169" @default.
• W1990436170 startingPage "163" @default.
• W1990436170 abstract "To evaluate the hypothesis that lymphocyte stimulation can modify the bronchoconstrictive response to inhalational challenge with an allergen, we administered interleukin-2 (IL-2), an important lymphokine in lymphocyte activation and proliferation, to actively sensitized rats. Brown Norway rats received either human recombinant IL-2 (n = 8) or its vehicle (n = 7) twice a day from the ninth to the fourteenth day after active sensitization to ovalbumin (OA) and were challenged with an aerosol of OA. Lung resistance (Rl) during the early response increased to a maximum of 698 ± 230% and 180 ± 26% of baseline values in the animals receiving IL-2 and vehicle, respectively (p < 0.025). The late response was threefold greater in IL-2-treated than in vehicle-treated animals (p = 0.01). IL-2 increased OA-specific IgG levels in the serum, but it did not significantly affect total or specific IgE levels. IL-2 caused an inflammatory infiltrate around the airways with significant increases in eosinophils, lymphocytes, and mast cells prior to antigen challenge. Our results indicate that stimulation of cell-mediated immunity can affect airway responsiveness to antigen." @default.
• W1990436170 created "2016-06-24" @default.
• W1990436170 creator A5006440043 @default.
• W1990436170 creator A5022260354 @default.
• W1990436170 creator A5045923783 @default.
• W1990436170 creator A5048737172 @default.
• W1990436170 creator A5049755846 @default.
• W1990436170 creator A5075006568 @default.
• W1990436170 creator A5083914935 @default.
• W1990436170 date "1992-07-01" @default.
• W1990436170 modified "2023-09-23" @default.
• W1990436170 title "Effect of Interleukin-2 on the Airway Response to Antigen in the Rat" @default.
• W1990436170 cites W1978972285 @default.
• W1990436170 cites W1979415936 @default.
• W1990436170 cites W2005554268 @default.
• W1990436170 cites W2013737722 @default.
• W1990436170 cites W2067364660 @default.
• W1990436170 cites W2072495699 @default.
• W1990436170 cites W2095905668 @default.
• W1990436170 cites W2109738251 @default.
• W1990436170 cites W2131721083 @default.
• W1990436170 cites W2150988478 @default.
• W1990436170 cites W2153380585 @default.
• W1990436170 cites W2338760211 @default.
• W1990436170 cites W2339764534 @default.
• W1990436170 doi "https://doi.org/10.1164/ajrccm/146.1.163" @default.
• W1990436170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1626798" @default.
• W1990436170 hasPublicationYear "1992" @default.
• W1990436170 type Work @default.
• W1990436170 sameAs 1990436170 @default.
• W1990436170 citedByCount "47" @default.
• W1990436170 countsByYear W19904361702012 @default.
• W1990436170 countsByYear W19904361702017 @default.
• W1990436170 countsByYear W19904361702022 @default.
• W1990436170 crossrefType "journal-article" @default.
• W1990436170 hasAuthorship W1990436170A5006440043 @default.
• W1990436170 hasAuthorship W1990436170A5022260354 @default.
• W1990436170 hasAuthorship W1990436170A5045923783 @default.
• W1990436170 hasAuthorship W1990436170A5048737172 @default.
• W1990436170 hasAuthorship W1990436170A5049755846 @default.
• W1990436170 hasAuthorship W1990436170A5075006568 @default.
• W1990436170 hasAuthorship W1990436170A5083914935 @default.
• W1990436170 hasConcept C134018914 @default.
• W1990436170 hasConcept C141105273 @default.
• W1990436170 hasConcept C147483822 @default.
• W1990436170 hasConcept C159654299 @default.
• W1990436170 hasConcept C191732599 @default.
• W1990436170 hasConcept C203014093 @default.
• W1990436170 hasConcept C24998067 @default.
• W1990436170 hasConcept C2776042228 @default.
• W1990436170 hasConcept C2776217527 @default.
• W1990436170 hasConcept C2776946954 @default.
• W1990436170 hasConcept C2777371288 @default.
• W1990436170 hasConcept C2777761686 @default.
• W1990436170 hasConcept C2778690821 @default.
• W1990436170 hasConcept C2780769369 @default.
• W1990436170 hasConcept C33362165 @default.
• W1990436170 hasConcept C49382859 @default.
• W1990436170 hasConcept C71924100 @default.
• W1990436170 hasConcept C74172505 @default.
• W1990436170 hasConcept C8891405 @default.
• W1990436170 hasConceptScore W1990436170C134018914 @default.
• W1990436170 hasConceptScore W1990436170C141105273 @default.
• W1990436170 hasConceptScore W1990436170C147483822 @default.
• W1990436170 hasConceptScore W1990436170C159654299 @default.
• W1990436170 hasConceptScore W1990436170C191732599 @default.
• W1990436170 hasConceptScore W1990436170C203014093 @default.
• W1990436170 hasConceptScore W1990436170C24998067 @default.
• W1990436170 hasConceptScore W1990436170C2776042228 @default.
• W1990436170 hasConceptScore W1990436170C2776217527 @default.
• W1990436170 hasConceptScore W1990436170C2776946954 @default.
• W1990436170 hasConceptScore W1990436170C2777371288 @default.
• W1990436170 hasConceptScore W1990436170C2777761686 @default.
• W1990436170 hasConceptScore W1990436170C2778690821 @default.
• W1990436170 hasConceptScore W1990436170C2780769369 @default.
• W1990436170 hasConceptScore W1990436170C33362165 @default.
• W1990436170 hasConceptScore W1990436170C49382859 @default.
• W1990436170 hasConceptScore W1990436170C71924100 @default.
• W1990436170 hasConceptScore W1990436170C74172505 @default.
• W1990436170 hasConceptScore W1990436170C8891405 @default.
• W1990436170 hasIssue "1" @default.
• W1990436170 hasLocation W19904361701 @default.
• W1990436170 hasLocation W19904361702 @default.
• W1990436170 hasOpenAccess W1990436170 @default.
• W1990436170 hasPrimaryLocation W19904361701 @default.
• W1990436170 hasRelatedWork W1789803423 @default.
• W1990436170 hasRelatedWork W1975985310 @default.
• W1990436170 hasRelatedWork W1990436170 @default.
• W1990436170 hasRelatedWork W2029245561 @default.
• W1990436170 hasRelatedWork W2047297229 @default.
• W1990436170 hasRelatedWork W2099512139 @default.
• W1990436170 hasRelatedWork W2410833002 @default.
• W1990436170 hasRelatedWork W24425141 @default.
• W1990436170 hasRelatedWork W2562974677 @default.
• W1990436170 hasRelatedWork W3212012594 @default.
• W1990436170 hasVolume "146" @default.
• W1990436170 isParatext "false" @default.
• W1990436170 isRetracted "false" @default.

• next