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• W1990444637 abstract "The Saccharomyces cerevisiae MEF2 gene is a mitochondrial protein translation factor. Formerly believed to catalyze peptide elongation, evidence now suggests its involvement in ribosome recycling. This study confirms the role of the MEF2 gene for cell respiration and further uncovers a slow growth phenotype and reduced chronological lifespan. Furthermore, in comparison with cytoplasmic ρ(0) strains, mef2Δ strains have a marked reduction of the inner mitochondrial membrane potential and mitochondria show a tendency to aggregate, suggesting an additional role for the MEF2 gene in maintenance of mitochondrial health, a role that may also be shared by other mitochondrial protein synthesis factors." @default.
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• W1990444637 date "2011-03-15" @default.
• W1990444637 modified "2023-09-25" @default.
• W1990444637 title "The<i>MEF2</i>gene is essential for yeast longevity, with a dual role in cell respiration and maintenance of mitochondrial membrane potential" @default.
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• W1990444637 doi "https://doi.org/10.1016/j.febslet.2011.03.022" @default.
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