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- W1990457541 abstract "POEMS syndrome is a rare plasma cell disorder characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes associated with multiorgan involvement. The pathogenesis of POEMS syndrome is not well understood; however, overproduction of vascular endothelial growth factor (VEGF), probably secreted by plasma cells, has been considered responsible.1,2 Treatment was largely unsuccessful until the past decade.3,4 More recently, considerable progress has been made in interpreting the pathogenesis, clinical features, and diagnosis, and new treatment options have become available, including novel agents such as thalidomide, lenalidomide, and bortezomib, anti-VEGF antibody, and autologous stem cell transplantation (ASCT)." @default.
- W1990457541 created "2016-06-24" @default.
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- W1990457541 date "2014-02-01" @default.
- W1990457541 modified "2023-09-26" @default.
- W1990457541 title "Autologous Stem Cell Transplantation for POEMS Syndrome" @default.
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- W1990457541 doi "https://doi.org/10.1016/j.clml.2013.12.009" @default.
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