Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990482826> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1990482826 endingPage "4" @default.
- W1990482826 startingPage "1" @default.
- W1990482826 abstract "Abstract Chloroquine sulphate (CQS) is a water-soluble anti-malarial drug having blood schizontocidal activity against Plasmodium falciparum, P. ovale, P. vivax and P. malarine . It has been reported that the lipid-soluble chloroquine base, which has similar anti-malarial and other biochemical effects, rigidifies (orders) the liposomal membrane in vivo. Here, in order to examine the lipid perturbation mechanism of CQS, we have studied the effect of incorporation of this drug into the liposomal membrane of dipalmitoyl phosphatidylcholine as measured by the fluorescence polarization of the membrane-embedded probe, 1,6-diphenyl-1,3,5-hexatriene. Our results show that the drug CQS also rigidifies the liposomal membrane even though the mechanism of the drug metabolism in vivo plays an important role. Probably the anti-malarial and other biochemical effects of CQS are exercised through this membrane rigidification." @default.
- W1990482826 created "2016-06-24" @default.
- W1990482826 creator A5001325041 @default.
- W1990482826 creator A5071043124 @default.
- W1990482826 creator A5086764649 @default.
- W1990482826 date "1995-02-01" @default.
- W1990482826 modified "2023-10-16" @default.
- W1990482826 title "Lipid perturbation of liposomal membrane of dipalmitoyl phosphatidylcholine by chloroquine sulphate — a fluorescence anisotropic study" @default.
- W1990482826 cites W1966769024 @default.
- W1990482826 cites W1968489857 @default.
- W1990482826 cites W1979853147 @default.
- W1990482826 cites W1989575165 @default.
- W1990482826 cites W2002660914 @default.
- W1990482826 cites W2038270897 @default.
- W1990482826 cites W2085966459 @default.
- W1990482826 cites W2125505240 @default.
- W1990482826 doi "https://doi.org/10.1016/0927-7765(94)01155-x" @default.
- W1990482826 hasPublicationYear "1995" @default.
- W1990482826 type Work @default.
- W1990482826 sameAs 1990482826 @default.
- W1990482826 citedByCount "15" @default.
- W1990482826 countsByYear W19904828262012 @default.
- W1990482826 countsByYear W19904828262019 @default.
- W1990482826 countsByYear W19904828262021 @default.
- W1990482826 countsByYear W19904828262023 @default.
- W1990482826 crossrefType "journal-article" @default.
- W1990482826 hasAuthorship W1990482826A5001325041 @default.
- W1990482826 hasAuthorship W1990482826A5071043124 @default.
- W1990482826 hasAuthorship W1990482826A5086764649 @default.
- W1990482826 hasConcept C111357860 @default.
- W1990482826 hasConcept C120665830 @default.
- W1990482826 hasConcept C121332964 @default.
- W1990482826 hasConcept C122398194 @default.
- W1990482826 hasConcept C12554922 @default.
- W1990482826 hasConcept C142724271 @default.
- W1990482826 hasConcept C185154212 @default.
- W1990482826 hasConcept C185592680 @default.
- W1990482826 hasConcept C2776330855 @default.
- W1990482826 hasConcept C2777425658 @default.
- W1990482826 hasConcept C2778048844 @default.
- W1990482826 hasConcept C2778918659 @default.
- W1990482826 hasConcept C39944091 @default.
- W1990482826 hasConcept C41625074 @default.
- W1990482826 hasConcept C43617362 @default.
- W1990482826 hasConcept C55493867 @default.
- W1990482826 hasConcept C71924100 @default.
- W1990482826 hasConcept C85725439 @default.
- W1990482826 hasConcept C86803240 @default.
- W1990482826 hasConcept C91881484 @default.
- W1990482826 hasConceptScore W1990482826C111357860 @default.
- W1990482826 hasConceptScore W1990482826C120665830 @default.
- W1990482826 hasConceptScore W1990482826C121332964 @default.
- W1990482826 hasConceptScore W1990482826C122398194 @default.
- W1990482826 hasConceptScore W1990482826C12554922 @default.
- W1990482826 hasConceptScore W1990482826C142724271 @default.
- W1990482826 hasConceptScore W1990482826C185154212 @default.
- W1990482826 hasConceptScore W1990482826C185592680 @default.
- W1990482826 hasConceptScore W1990482826C2776330855 @default.
- W1990482826 hasConceptScore W1990482826C2777425658 @default.
- W1990482826 hasConceptScore W1990482826C2778048844 @default.
- W1990482826 hasConceptScore W1990482826C2778918659 @default.
- W1990482826 hasConceptScore W1990482826C39944091 @default.
- W1990482826 hasConceptScore W1990482826C41625074 @default.
- W1990482826 hasConceptScore W1990482826C43617362 @default.
- W1990482826 hasConceptScore W1990482826C55493867 @default.
- W1990482826 hasConceptScore W1990482826C71924100 @default.
- W1990482826 hasConceptScore W1990482826C85725439 @default.
- W1990482826 hasConceptScore W1990482826C86803240 @default.
- W1990482826 hasConceptScore W1990482826C91881484 @default.
- W1990482826 hasIssue "1" @default.
- W1990482826 hasLocation W19904828261 @default.
- W1990482826 hasOpenAccess W1990482826 @default.
- W1990482826 hasPrimaryLocation W19904828261 @default.
- W1990482826 hasRelatedWork W1972343240 @default.
- W1990482826 hasRelatedWork W1990482826 @default.
- W1990482826 hasRelatedWork W2033588568 @default.
- W1990482826 hasRelatedWork W2034684169 @default.
- W1990482826 hasRelatedWork W2064011811 @default.
- W1990482826 hasRelatedWork W2093068573 @default.
- W1990482826 hasRelatedWork W2177354548 @default.
- W1990482826 hasRelatedWork W2465801395 @default.
- W1990482826 hasRelatedWork W3011024476 @default.
- W1990482826 hasRelatedWork W4246432387 @default.
- W1990482826 hasVolume "4" @default.
- W1990482826 isParatext "false" @default.
- W1990482826 isRetracted "false" @default.
- W1990482826 magId "1990482826" @default.
- W1990482826 workType "article" @default.