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• W1990490126 abstract "Exposure of 28 day old rats to moderate hypoxia (10% oxygen) for three weeks led to significant increases of immunoreactive levels of substance P and met-enkephalin in the substantia nigra but not in the corpus striatum, globus pallidus of hypothalamus. A similar group of animals exposed to hypoxia for three weeks showed decreased angiotensin converting enzyme activity in the corpus striatum and substantia nigra and decreased GABA levels in the substantia nigra. However, fifteen days after recovery from hypoxia these changes were no longer apparent. Exposure to chronic, moderate hypoxia can affect levels of putative neurotransmitters in the brain, and based on the present findings the substantia nigra or the striato-nigral pathways appear to be particularly vulnerable." @default.
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• W1990490126 date "1981-06-01" @default.
• W1990490126 modified "2023-09-25" @default.
• W1990490126 title "Neurochemical studies in the hypoxic brain: Substance P, met-enkephalin, GABA and angiotensin converting enzyme" @default.
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• W1990490126 doi "https://doi.org/10.1016/0024-3205(81)90268-x" @default.
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