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- W1990492046 abstract "Ionizing radiation and a variety of genetic conditions are thought to explain 5–10% of childhood cancers. Infection with Epstein–Barr virus (EBV) in parts of Africa and human immunodeficiency virus (HIV) increase the risk of Burkitt's lymphoma and Kaposi's sarcoma, respectively. Other risk factors have not been conclusively identified. A review of the data on international variation in incidence, recent changes in incidence, and risk factors suggests that many childhood cancers are likely to have nongenetic causes. The pattern of international variation and associations with surrogates of infection suggest an infectious etiology for acute lymphoblastic leukemia, although no agent has been identified. The biologic plausibility is strong that maternal consumption of food containing DNA topoisomerase II inhibitors may increase the risk of acute myeloid leukemia, although the data are limited now. For brain tumors, cured meats, polyomaviruses, and farm exposures may have etiologic roles. Changes in the incidence and characteristics of children with hepatoblastoma as well as risk factor studies suggest a role for an exposure of very low birth weight babies. High birth weight, tea or coffee consumption, and certain paternal occupations have shown some consistency in their association with Wilms' tumor. For most of the other cancers, very few epidemiologic studies have been conducted, so it is not surprising that nongenetic risk factors have not been detected. The most important difference between the cancers for which there are good etiologic clues and those for which there are not may be the number of relevant studies." @default.
- W1990492046 created "2016-06-24" @default.
- W1990492046 creator A5027785317 @default.
- W1990492046 date "2004-09-01" @default.
- W1990492046 modified "2023-10-16" @default.
- W1990492046 title "Nongenetic causes of childhood cancers: evidence from international variation, time trends, and risk factor studies" @default.
- W1990492046 cites W1479808598 @default.
- W1990492046 cites W1509299215 @default.
- W1990492046 cites W1562139353 @default.
- W1990492046 cites W1579765816 @default.
- W1990492046 cites W1679588982 @default.
- W1990492046 cites W1811884632 @default.
- W1990492046 cites W1911943950 @default.
- W1990492046 cites W1948776789 @default.
- W1990492046 cites W1957106694 @default.
- W1990492046 cites W1969041059 @default.
- W1990492046 cites W1969608508 @default.
- W1990492046 cites W1971494627 @default.
- W1990492046 cites W1972208213 @default.
- W1990492046 cites W1974412402 @default.
- W1990492046 cites W1978142981 @default.
- W1990492046 cites W1978257178 @default.
- W1990492046 cites W1979070977 @default.
- W1990492046 cites W1982194643 @default.
- W1990492046 cites W1983314289 @default.
- W1990492046 cites W1987372999 @default.
- W1990492046 cites W1988646031 @default.
- W1990492046 cites W1989851932 @default.
- W1990492046 cites W1990863885 @default.
- W1990492046 cites W1993666707 @default.
- W1990492046 cites W1997915780 @default.
- W1990492046 cites W2000257361 @default.
- W1990492046 cites W2000259265 @default.
- W1990492046 cites W2007500131 @default.
- W1990492046 cites W2007532842 @default.
- W1990492046 cites W2013413812 @default.
- W1990492046 cites W2014401052 @default.
- W1990492046 cites W2014551603 @default.
- W1990492046 cites W2018118917 @default.
- W1990492046 cites W2019034957 @default.
- W1990492046 cites W2019109618 @default.
- W1990492046 cites W2019268752 @default.
- W1990492046 cites W2022645679 @default.
- W1990492046 cites W2025095916 @default.
- W1990492046 cites W2029995565 @default.
- W1990492046 cites W2036114122 @default.
- W1990492046 cites W2042864409 @default.
- W1990492046 cites W2046403108 @default.
- W1990492046 cites W2050296508 @default.
- W1990492046 cites W2051148900 @default.
- W1990492046 cites W2055027051 @default.
- W1990492046 cites W2059449165 @default.
- W1990492046 cites W2062421077 @default.
- W1990492046 cites W2063644025 @default.
- W1990492046 cites W2066769922 @default.
- W1990492046 cites W2068158287 @default.
- W1990492046 cites W2071574372 @default.
- W1990492046 cites W2077858999 @default.
- W1990492046 cites W2088868608 @default.
- W1990492046 cites W2088927920 @default.
- W1990492046 cites W2094804309 @default.
- W1990492046 cites W2095075675 @default.
- W1990492046 cites W2095276325 @default.
- W1990492046 cites W2099742439 @default.
- W1990492046 cites W2103706664 @default.
- W1990492046 cites W2112604170 @default.
- W1990492046 cites W2114694923 @default.
- W1990492046 cites W2117402371 @default.
- W1990492046 cites W2129107096 @default.
- W1990492046 cites W2130714065 @default.
- W1990492046 cites W2131768915 @default.
- W1990492046 cites W2138819243 @default.
- W1990492046 cites W2142249587 @default.
- W1990492046 cites W2148570566 @default.
- W1990492046 cites W2149384322 @default.
- W1990492046 cites W2155532314 @default.
- W1990492046 cites W2161927091 @default.
- W1990492046 cites W2163337722 @default.
- W1990492046 cites W2165908993 @default.
- W1990492046 cites W2168456803 @default.
- W1990492046 cites W2168881809 @default.
- W1990492046 cites W2169278972 @default.
- W1990492046 cites W2169377833 @default.
- W1990492046 cites W2169418783 @default.
- W1990492046 cites W2169867898 @default.
- W1990492046 cites W2171128838 @default.
- W1990492046 cites W2172063734 @default.
- W1990492046 cites W2303549362 @default.
- W1990492046 cites W2320188351 @default.
- W1990492046 cites W4250473507 @default.
- W1990492046 doi "https://doi.org/10.1016/j.taap.2003.12.028" @default.
- W1990492046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15313582" @default.
- W1990492046 hasPublicationYear "2004" @default.
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