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- W1990498984 abstract "1. Observations have been made on the electrocardiographic effects of intravenous acetylstrophanthidin (0.056–0.180 mg/kg) in 20 studies on 13 mongrel dogs. 2. Acetylstrophanthidin exhibits digitalis-like effects and is considered a mest valuable laboratory tool. This is an important consideration where deterioration of animal preparations is an ever-present problem. 3. The onset of vagal response was independent of the dose of acetylstrophanthidin, and a return to control rates occurred within 10–30 minutes after injection. The reduction in rate was more obvious in the lower dose range and was obscured by arrhythmias above a dose of 0.082 mg./kg. 4. S-T and T wave changes without toxic manifestations occurred between doses of 0.062–0.082 mg/kg, and this is considered the probable optimal dose for the normal dog." @default.
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- W1990498984 date "1960-11-01" @default.
- W1990498984 modified "2023-10-14" @default.
- W1990498984 title "The electrocardiographic effects of acetylstrophanthidin in the normal dog" @default.
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- W1990498984 doi "https://doi.org/10.1016/0041-008x(60)90080-6" @default.
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