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- W1990502771 endingPage "662" @default.
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- W1990502771 abstract "Imatinib mesylate is a tyrosine kinase inhibitor that targets the BCR-ABL, c-kit, and PDGF (platelet-derived growth factor) receptors. Imatinib is mainly indicated for chronic myeloid leukemia and gastrointestinal stromal tumors but is also prescribed by dermatologists for dermatofibrosarcoma protuberans, systemic sclerosis, and systemic mastocytosis, among other conditions. Most adverse effects are mild or moderate and therapy is generally well tolerated. Adverse skin effects are very common and include nonspecific manifestations such as edema and maculopapular rashes or eruptions of diverse types (lichenoid or psoriasiform lesions, acute generalized exanthematic pustulosis, Stevens-Johnson syndrome, and more). Identifying and properly treating these reactions can help optimize adherence to treatment and improve the prognosis of the underlying disease." @default.
- W1990502771 created "2016-06-24" @default.
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- W1990502771 date "2014-09-01" @default.
- W1990502771 modified "2023-10-10" @default.
- W1990502771 title "Efectos adversos cutáneos del imatinib (inhibidor de la tirosín cinasa)" @default.
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- W1990502771 doi "https://doi.org/10.1016/j.ad.2013.01.009" @default.
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