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- W1990532852 abstract "The effect of inorganic mercury on the integrity of the endothelium of isolated bullfrog (Rana catesbeiana) corneas was examined by spectrophotometric analysis of corneal uptake of the vital stain Janus green, and by both transmission (TEM) and scanning (SEM) electron microscopy. The uptake of Janus green by the endothelium is dose related between 1·0 and 30·0 μM HgCl2. The effect of mercury is not altered by changes in external calcium concentration, nor is it influenced by the calcium ionophore A23187. indicating that inorganic mercury damages the corneal endothelium through a mechanism which does not involve competition with external calcium or interaction with calcium channels. TEM and SEM demonstrate significant ultrastructural damage to the endothelium exposed to inorganic mercury, including cellular swelling, increased vacuolization, focal denuding of Descemet's membrane, and diminished integrity at the intercellular junctions." @default.
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- W1990532852 date "1993-11-01" @default.
- W1990532852 modified "2023-10-18" @default.
- W1990532852 title "Low Levels of Inorganic Mercury Damage the Corneal Endothelium" @default.
- W1990532852 doi "https://doi.org/10.1006/exer.1993.1159" @default.
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