FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990568669> ?p ?o ?g. }

• W1990568669 abstract "Agarwood (Aquilaria sinensis), well known as incense in Southeast Asia, has been used as a digestive in traditional medicine. We investigated the laxative effects of an ethanol extract of agarwood leaves (EEA) in a rat model of low-fiber diet-induced constipation.A set of rats was bred on a normal diet while another set was placed on a low-fiber diet to induce constipation. The laxative effect of agarwood was then investigated on both sets of rats.Pretreatment of normal rats with single dose of EEA (600 mg/kg, p.o.) significantly increased frequency and weight of stools. Also, treatments with EEA (300 and 600 mg/kg, p.o.) for 14 days caused a significant increase in stool frequency and weight. Feeding of the animals with a low-fiber diet resulted in a decrease in stool weight, frequency, and water content and also delayed carmine egestion. A single treatment with EEA (600 mg/kg) or senna (150 and 300 mg/kg) significantly increased stool frequency, weight, and water content and also accelerated carmine egestion in the model rats. Once daily administrations of EEA (150 mg/kg), for 14 days, caused a significant increase in water content of stools. The higher doses of EEA (300 and 600 mg/kg) significantly increased frequency, weight, and water content of the stools while accelerating carmine egestion in the constipated rats. Senna (150 and 300 mg/kg) produced similar effect as the higher doses of EEA but, in addition, induced severe diarrhea.These findings indicate that EEA has a laxative effect, without causing diarrhea, in a rat model of low-fiber diet-induced constipation. These findings suggest that EEA may be highly effective on constipation as a complementary medicine in humans suffering from life style-induced constipation." @default.
• W1990568669 created "2016-06-24" @default.
• W1990568669 creator A5003735953 @default.
• W1990568669 creator A5017178409 @default.
• W1990568669 creator A5018954591 @default.
• W1990568669 creator A5054508699 @default.
• W1990568669 creator A5069944428 @default.
• W1990568669 creator A5079176935 @default.
• W1990568669 creator A5084258671 @default.
• W1990568669 date "2010-11-15" @default.
• W1990568669 modified "2023-10-18" @default.
• W1990568669 title "Laxative effects of agarwood on low-fiber diet-induced constipation in rats" @default.
• W1990568669 cites W1976304803 @default.
• W1990568669 cites W2017740517 @default.
• W1990568669 cites W2019770105 @default.
• W1990568669 cites W2073281532 @default.
• W1990568669 cites W2104710488 @default.
• W1990568669 cites W2169785683 @default.
• W1990568669 doi "https://doi.org/10.1186/1472-6882-10-68" @default.
• W1990568669 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2995776" @default.
• W1990568669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21078136" @default.
• W1990568669 hasPublicationYear "2010" @default.
• W1990568669 type Work @default.
• W1990568669 sameAs 1990568669 @default.
• W1990568669 citedByCount "73" @default.
• W1990568669 countsByYear W19905686692012 @default.
• W1990568669 countsByYear W19905686692013 @default.
• W1990568669 countsByYear W19905686692014 @default.
• W1990568669 countsByYear W19905686692015 @default.
• W1990568669 countsByYear W19905686692016 @default.
• W1990568669 countsByYear W19905686692017 @default.
• W1990568669 countsByYear W19905686692018 @default.
• W1990568669 countsByYear W19905686692019 @default.
• W1990568669 countsByYear W19905686692020 @default.
• W1990568669 countsByYear W19905686692021 @default.
• W1990568669 countsByYear W19905686692022 @default.
• W1990568669 countsByYear W19905686692023 @default.
• W1990568669 crossrefType "journal-article" @default.
• W1990568669 hasAuthorship W1990568669A5003735953 @default.
• W1990568669 hasAuthorship W1990568669A5017178409 @default.
• W1990568669 hasAuthorship W1990568669A5018954591 @default.
• W1990568669 hasAuthorship W1990568669A5054508699 @default.
• W1990568669 hasAuthorship W1990568669A5069944428 @default.
• W1990568669 hasAuthorship W1990568669A5079176935 @default.
• W1990568669 hasAuthorship W1990568669A5084258671 @default.
• W1990568669 hasBestOaLocation W19905686691 @default.
• W1990568669 hasConcept C126322002 @default.
• W1990568669 hasConcept C140793950 @default.
• W1990568669 hasConcept C142724271 @default.
• W1990568669 hasConcept C204787440 @default.
• W1990568669 hasConcept C2778706202 @default.
• W1990568669 hasConcept C2779456107 @default.
• W1990568669 hasConcept C2779802037 @default.
• W1990568669 hasConcept C2780661987 @default.
• W1990568669 hasConcept C2781112942 @default.
• W1990568669 hasConcept C2992741425 @default.
• W1990568669 hasConcept C31903555 @default.
• W1990568669 hasConcept C556039675 @default.
• W1990568669 hasConcept C61716771 @default.
• W1990568669 hasConcept C71527416 @default.
• W1990568669 hasConcept C71924100 @default.
• W1990568669 hasConcept C86803240 @default.
• W1990568669 hasConcept C89423630 @default.
• W1990568669 hasConcept C90924648 @default.
• W1990568669 hasConceptScore W1990568669C126322002 @default.
• W1990568669 hasConceptScore W1990568669C140793950 @default.
• W1990568669 hasConceptScore W1990568669C142724271 @default.
• W1990568669 hasConceptScore W1990568669C204787440 @default.
• W1990568669 hasConceptScore W1990568669C2778706202 @default.
• W1990568669 hasConceptScore W1990568669C2779456107 @default.
• W1990568669 hasConceptScore W1990568669C2779802037 @default.
• W1990568669 hasConceptScore W1990568669C2780661987 @default.
• W1990568669 hasConceptScore W1990568669C2781112942 @default.
• W1990568669 hasConceptScore W1990568669C2992741425 @default.
• W1990568669 hasConceptScore W1990568669C31903555 @default.
• W1990568669 hasConceptScore W1990568669C556039675 @default.
• W1990568669 hasConceptScore W1990568669C61716771 @default.
• W1990568669 hasConceptScore W1990568669C71527416 @default.
• W1990568669 hasConceptScore W1990568669C71924100 @default.
• W1990568669 hasConceptScore W1990568669C86803240 @default.
• W1990568669 hasConceptScore W1990568669C89423630 @default.
• W1990568669 hasConceptScore W1990568669C90924648 @default.
• W1990568669 hasIssue "1" @default.
• W1990568669 hasLocation W19905686691 @default.
• W1990568669 hasLocation W19905686692 @default.
• W1990568669 hasLocation W19905686693 @default.
• W1990568669 hasLocation W19905686694 @default.
• W1990568669 hasLocation W19905686695 @default.
• W1990568669 hasOpenAccess W1990568669 @default.
• W1990568669 hasPrimaryLocation W19905686691 @default.
• W1990568669 hasRelatedWork W1965054756 @default.
• W1990568669 hasRelatedWork W1989721370 @default.
• W1990568669 hasRelatedWork W1990568669 @default.
• W1990568669 hasRelatedWork W2034116737 @default.
• W1990568669 hasRelatedWork W2127322655 @default.
• W1990568669 hasRelatedWork W2761192601 @default.
• W1990568669 hasRelatedWork W2997597874 @default.
• W1990568669 hasRelatedWork W3174572362 @default.
• W1990568669 hasRelatedWork W4205784026 @default.
• W1990568669 hasRelatedWork W4211257801 @default.

• next