FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990570727> ?p ?o ?g. }

• W1990570727 endingPage "3228" @default.
• W1990570727 startingPage "3222" @default.
• W1990570727 abstract "Abstract This prospective study compared diagnostic and prognostic value of conventional cytologic (CC) examination and flow cytometry (FCM) of baseline samples of cerebrospinal fluid (CSF) in 174 patients with newly diagnosed aggressive non-Hodgkin lymphoma (NHL). FCM detected a neoplastic population in the CSF of 18 of 174 patients (10%), CC only in 7 (4%; P < .001); 11 patients (14%) were discordant (FCM+/CC−). At a median follow-up of 46 months, there were 64 systemic progressions and 10 CNS relapses, including 2 patients with both systemic and CNS relapses. Two-year progression-free and overall survival were significantly higher in patients with FCM− CSF (62% and 72%) compared with those FCM+ CSF (39% and 50%, respectively), with a 2-year CNS relapse cumulative incidence of 3% (95% confidence interval [CI], 0-7) versus 17% (95% CI, 0-34; P = .004), respectively. The risk of CNS progression was significantly higher in FMC+/CC− versus FCM−/CC− patients (hazard ratio = 8.16, 95% CI, 1.45-46). In conclusion, FCM positivity in the CSF of patients with high-risk NHL is associated with a significantly higher CNS relapse risk and poorer outcome. The combination of IV drugs with a higher CNS bioavailability and intrathecal chemotherapy is advisable to prevent CNS relapses in FCM+ patients." @default.
• W1990570727 created "2016-06-24" @default.
• W1990570727 creator A5005558035 @default.
• W1990570727 creator A5011614506 @default.
• W1990570727 creator A5012310310 @default.
• W1990570727 creator A5013142543 @default.
• W1990570727 creator A5026430732 @default.
• W1990570727 creator A5029318642 @default.
• W1990570727 creator A5032323700 @default.
• W1990570727 creator A5034220119 @default.
• W1990570727 creator A5058392949 @default.
• W1990570727 creator A5061736991 @default.
• W1990570727 creator A5063909411 @default.
• W1990570727 creator A5068506918 @default.
• W1990570727 creator A5069053301 @default.
• W1990570727 creator A5070003191 @default.
• W1990570727 creator A5081018862 @default.
• W1990570727 creator A5081879832 @default.
• W1990570727 creator A5083068356 @default.
• W1990570727 creator A5085410438 @default.
• W1990570727 creator A5088592707 @default.
• W1990570727 creator A5090179703 @default.
• W1990570727 date "2012-10-18" @default.
• W1990570727 modified "2023-09-28" @default.
• W1990570727 title "Final results of a multicenter trial addressing role of CSF flow cytometric analysis in NHL patients at high risk for CNS dissemination" @default.
• W1990570727 cites W173609426 @default.
• W1990570727 cites W190609963 @default.
• W1990570727 cites W1931431191 @default.
• W1990570727 cites W1972426904 @default.
• W1990570727 cites W1973617793 @default.
• W1990570727 cites W1975983122 @default.
• W1990570727 cites W1980474425 @default.
• W1990570727 cites W1982274007 @default.
• W1990570727 cites W1983480792 @default.
• W1990570727 cites W1983935384 @default.
• W1990570727 cites W1989398195 @default.
• W1990570727 cites W1995752649 @default.
• W1990570727 cites W2012451332 @default.
• W1990570727 cites W2016307324 @default.
• W1990570727 cites W2018071905 @default.
• W1990570727 cites W2038981426 @default.
• W1990570727 cites W2043212179 @default.
• W1990570727 cites W2058015212 @default.
• W1990570727 cites W2064223130 @default.
• W1990570727 cites W2072228041 @default.
• W1990570727 cites W2073140442 @default.
• W1990570727 cites W2076509494 @default.
• W1990570727 cites W2077554728 @default.
• W1990570727 cites W2084134345 @default.
• W1990570727 cites W2084386934 @default.
• W1990570727 cites W2089242301 @default.
• W1990570727 cites W2100305178 @default.
• W1990570727 cites W2100367991 @default.
• W1990570727 cites W2106928992 @default.
• W1990570727 cites W2107094261 @default.
• W1990570727 cites W2113971895 @default.
• W1990570727 cites W2131338392 @default.
• W1990570727 cites W2131818768 @default.
• W1990570727 cites W2135224106 @default.
• W1990570727 cites W2145304413 @default.
• W1990570727 cites W2147686446 @default.
• W1990570727 cites W2151883851 @default.
• W1990570727 cites W2152996672 @default.
• W1990570727 cites W2160305510 @default.
• W1990570727 cites W2166676098 @default.
• W1990570727 doi "https://doi.org/10.1182/blood-2012-04-423095" @default.
• W1990570727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22927246" @default.
• W1990570727 hasPublicationYear "2012" @default.
• W1990570727 type Work @default.
• W1990570727 sameAs 1990570727 @default.
• W1990570727 citedByCount "78" @default.
• W1990570727 countsByYear W19905707272013 @default.
• W1990570727 countsByYear W19905707272014 @default.
• W1990570727 countsByYear W19905707272015 @default.
• W1990570727 countsByYear W19905707272016 @default.
• W1990570727 countsByYear W19905707272017 @default.
• W1990570727 countsByYear W19905707272018 @default.
• W1990570727 countsByYear W19905707272019 @default.
• W1990570727 countsByYear W19905707272020 @default.
• W1990570727 countsByYear W19905707272021 @default.
• W1990570727 countsByYear W19905707272022 @default.
• W1990570727 countsByYear W19905707272023 @default.
• W1990570727 crossrefType "journal-article" @default.
• W1990570727 hasAuthorship W1990570727A5005558035 @default.
• W1990570727 hasAuthorship W1990570727A5011614506 @default.
• W1990570727 hasAuthorship W1990570727A5012310310 @default.
• W1990570727 hasAuthorship W1990570727A5013142543 @default.
• W1990570727 hasAuthorship W1990570727A5026430732 @default.
• W1990570727 hasAuthorship W1990570727A5029318642 @default.
• W1990570727 hasAuthorship W1990570727A5032323700 @default.
• W1990570727 hasAuthorship W1990570727A5034220119 @default.
• W1990570727 hasAuthorship W1990570727A5058392949 @default.
• W1990570727 hasAuthorship W1990570727A5061736991 @default.
• W1990570727 hasAuthorship W1990570727A5063909411 @default.
• W1990570727 hasAuthorship W1990570727A5068506918 @default.
• W1990570727 hasAuthorship W1990570727A5069053301 @default.
• W1990570727 hasAuthorship W1990570727A5070003191 @default.
• W1990570727 hasAuthorship W1990570727A5081018862 @default.

• next