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• W1990631452 abstract "Aims. Elevated pulse pressure (PP) has been reported to be a risk factor for type 2 diabetes in elderly patients with hypertension. Methods. Cross-sectional relationships of PP with known risk factors for type 2 diabetes and inflammatory markers were examined in 150 elderly community-dwelling women, 79 women (52.7%) of whom had hypertension. Results. Systolic blood pressure (standardized β , 0.775), log tumor necrosis factor- α (TNF- α , standardized β , 0.110), age (standardized β , 0.140), and neutrophil count (standardized β , 0.114) emerged as determinants of PP independent of high-sensitivity C-reactive protein, interleukin-6, monocyte count, plasminogen activator inhibitor-1, homeostasis model assessment of insulin resistance, HDL-cholesterol, and adiponectin (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>R</mml:mi></mml:mrow></mml:math> 2 = 0.772). Conclusions. The present studies have demonstrated an independent association of higher PP with higher TNF- α , a marker of insulin resistance, and neutrophil count in community-living elderly women and suggest that insulin resistance and chronic low-grade inflammation may in part be responsible for the association between high PP and incident type 2 diabetes found in elderly patients with hypertension." @default.
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• W1990631452 date "2014-01-01" @default.
• W1990631452 modified "2023-10-16" @default.
• W1990631452 title "Association of Pulse Pressure with Serum TNF-αand Neutrophil Count in the Elderly" @default.
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• W1990631452 doi "https://doi.org/10.1155/2014/972431" @default.
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