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• W1990653079 abstract "Whilst catalytic iron has been implicated in the development of atherosclerosis by initiating low density lipoprotein (LDL) oxidation, the source of such iron remains uncertain. Here, we show that LDL oxidation in the presence of ferritin was stimulated by ascorbate (15–60 μM) whilst this effect was inhibited by the iron chelator desferrioxamine. Ascorbate also showed an antioxidant activity at high concentrations (125–250 μM) Our results suggest that the combination of ascorbate with ferritin may supply free iron for LDL oxidation in vivo." @default.
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• W1990653079 date "1996-12-01" @default.
• W1990653079 modified "2023-09-26" @default.
• W1990653079 title "Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin" @default.
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• W1990653079 doi "https://doi.org/10.1016/s0005-2760(96)00121-x" @default.
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