FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990687637> ?p ?o ?g. }

• W1990687637 endingPage "1117" @default.
• W1990687637 startingPage "1109" @default.
• W1990687637 abstract "In DNA replication, DNA chains are generally initiated from small pieces of ribonucleotides attached to DNA templates. These 'primers' are synthesized by various enzymatic mechanisms in Escherichia coli. Studies on primer RNA synthesis on single-stranded DNA templates containing specific 'priming signals' revealed the presence of two distinct modes, ie immobile and mobile priming. The former includes primer RNA synthesis by primase encoded by dnaG and by RNA polymerase containing a sigma 70 subunit. Priming is initiated at a specific site in immobile priming. Novel immobile priming signals were identified from various plasmid replicons, some of which function in initiation of the leading strand synthesis. The latter, on the other hands involves a protein complex, primosome, which contains DnaB, the replicative helicase for E coli chromosomal replication. Utilizing the energy fueled by ATP hydrolysis of DnaB protein, primosomes are able to translocate on a template DNA and primase synthesizes primer RNAs at multiple sites. Two distinct primosomes, DnaA-dependent and PriA-dependent, have been identified, which are differentially utilized for E coli chromosomal replication. Whereas DnaA-dependent primosome supports normal chromosomal replication from oriC, the PriA-dependent primosome functions in oriC-independent chromosomal replication observed in DNA-damaged cells or cells lacking RNaseH activity. In oriC-independent replication, PriA protein may recognize the D- or R-loop structure, respectively, to initiate assembly of a primosome which mediates primer RNA synthesis and replication fork progression." @default.
• W1990687637 created "2016-06-24" @default.
• W1990687637 creator A5065692230 @default.
• W1990687637 creator A5082081122 @default.
• W1990687637 date "1996-01-01" @default.
• W1990687637 modified "2023-09-24" @default.
• W1990687637 title "Mechanisms of primer RNA synthesis and D-loop/R-loop-dependent DNA replication in Escherichia coli" @default.
• W1990687637 cites W148173028 @default.
• W1990687637 cites W1484866107 @default.
• W1990687637 cites W1489768032 @default.
• W1990687637 cites W1489835182 @default.
• W1990687637 cites W14977876 @default.
• W1990687637 cites W1498066542 @default.
• W1990687637 cites W1510329672 @default.
• W1990687637 cites W1511109772 @default.
• W1990687637 cites W1522284441 @default.
• W1990687637 cites W1537872391 @default.
• W1990687637 cites W1560669282 @default.
• W1990687637 cites W1583600685 @default.
• W1990687637 cites W1591954229 @default.
• W1990687637 cites W1596522081 @default.
• W1990687637 cites W1603916894 @default.
• W1990687637 cites W1630143373 @default.
• W1990687637 cites W1671632725 @default.
• W1990687637 cites W1955722333 @default.
• W1990687637 cites W1964317450 @default.
• W1990687637 cites W1977917428 @default.
• W1990687637 cites W1992075060 @default.
• W1990687637 cites W1993749221 @default.
• W1990687637 cites W2002760102 @default.
• W1990687637 cites W2004894981 @default.
• W1990687637 cites W2023528995 @default.
• W1990687637 cites W2043748488 @default.
• W1990687637 cites W2059960577 @default.
• W1990687637 cites W2059969446 @default.
• W1990687637 cites W2061135731 @default.
• W1990687637 cites W2077153159 @default.
• W1990687637 cites W2081945314 @default.
• W1990687637 cites W2083858189 @default.
• W1990687637 cites W2095256764 @default.
• W1990687637 cites W2102773702 @default.
• W1990687637 cites W2121001380 @default.
• W1990687637 cites W2137191431 @default.
• W1990687637 cites W2138997827 @default.
• W1990687637 cites W2140220147 @default.
• W1990687637 cites W2157429732 @default.
• W1990687637 cites W2173897158 @default.
• W1990687637 cites W2306853147 @default.
• W1990687637 cites W32943588 @default.
• W1990687637 cites W4236779320 @default.
• W1990687637 doi "https://doi.org/10.1016/s0300-9084(97)86737-5" @default.
• W1990687637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9150892" @default.
• W1990687637 hasPublicationYear "1996" @default.
• W1990687637 type Work @default.
• W1990687637 sameAs 1990687637 @default.
• W1990687637 citedByCount "19" @default.
• W1990687637 countsByYear W19906876372013 @default.
• W1990687637 countsByYear W19906876372015 @default.
• W1990687637 countsByYear W19906876372017 @default.
• W1990687637 countsByYear W19906876372020 @default.
• W1990687637 countsByYear W19906876372023 @default.
• W1990687637 crossrefType "journal-article" @default.
• W1990687637 hasAuthorship W1990687637A5065692230 @default.
• W1990687637 hasAuthorship W1990687637A5082081122 @default.
• W1990687637 hasConcept C104317684 @default.
• W1990687637 hasConcept C104690221 @default.
• W1990687637 hasConcept C107827726 @default.
• W1990687637 hasConcept C116107829 @default.
• W1990687637 hasConcept C153911025 @default.
• W1990687637 hasConcept C156719811 @default.
• W1990687637 hasConcept C161223559 @default.
• W1990687637 hasConcept C178790620 @default.
• W1990687637 hasConcept C185592680 @default.
• W1990687637 hasConcept C188036394 @default.
• W1990687637 hasConcept C188192080 @default.
• W1990687637 hasConcept C194830204 @default.
• W1990687637 hasConcept C2756471 @default.
• W1990687637 hasConcept C2777563447 @default.
• W1990687637 hasConcept C41141232 @default.
• W1990687637 hasConcept C54355233 @default.
• W1990687637 hasConcept C552990157 @default.
• W1990687637 hasConcept C58337764 @default.
• W1990687637 hasConcept C66072924 @default.
• W1990687637 hasConcept C67705224 @default.
• W1990687637 hasConcept C73573662 @default.
• W1990687637 hasConcept C86803240 @default.
• W1990687637 hasConcept C98086919 @default.
• W1990687637 hasConceptScore W1990687637C104317684 @default.
• W1990687637 hasConceptScore W1990687637C104690221 @default.
• W1990687637 hasConceptScore W1990687637C107827726 @default.
• W1990687637 hasConceptScore W1990687637C116107829 @default.
• W1990687637 hasConceptScore W1990687637C153911025 @default.
• W1990687637 hasConceptScore W1990687637C156719811 @default.
• W1990687637 hasConceptScore W1990687637C161223559 @default.
• W1990687637 hasConceptScore W1990687637C178790620 @default.
• W1990687637 hasConceptScore W1990687637C185592680 @default.
• W1990687637 hasConceptScore W1990687637C188036394 @default.
• W1990687637 hasConceptScore W1990687637C188192080 @default.

• next