Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990692227> ?p ?o ?g. }
- W1990692227 endingPage "1127" @default.
- W1990692227 startingPage "1121" @default.
- W1990692227 abstract "In this work the synthesis and antiparasitical activity of new 1,5-diaryl-3-oxo-1,4-pentadienyl derivatives are described. First, compounds 1a, 1b, 1c and 1d were prepared by acid-catalyzed aldol reaction between 2-butanone and benzaldehyde, anisaldehyde, p-N,N-dimethylaminobenzaldehyde and p-nitrobenzaldehyde. Reacting each of the methyl ketones 1a, 1b, 1c and 1d with the p-substituted benzaldehydes under basic-catalyzed aldol reaction, we further prepared compounds 2a-2p. All twenty compounds were evaluated for antiproliferative activity, particularly for promastigote of Leishmania amazonensis and epimastigote of Trypanosoma cruzi. All compounds showed good activity while nitro compounds 2i and 2k showed inhibition activity at a few μM." @default.
- W1990692227 created "2016-06-24" @default.
- W1990692227 creator A5015862647 @default.
- W1990692227 creator A5021372943 @default.
- W1990692227 creator A5033881429 @default.
- W1990692227 creator A5038629290 @default.
- W1990692227 creator A5038956975 @default.
- W1990692227 creator A5039475493 @default.
- W1990692227 creator A5040902002 @default.
- W1990692227 creator A5042214848 @default.
- W1990692227 creator A5090002492 @default.
- W1990692227 date "2014-02-01" @default.
- W1990692227 modified "2023-10-17" @default.
- W1990692227 title "Unsymmetrical 1,5-diaryl-3-oxo-1,4-pentadienyls and their evaluation as antiparasitic agents" @default.
- W1990692227 cites W103706122 @default.
- W1990692227 cites W1489144062 @default.
- W1990692227 cites W1502851346 @default.
- W1990692227 cites W1670463471 @default.
- W1990692227 cites W1998207862 @default.
- W1990692227 cites W2000104422 @default.
- W1990692227 cites W2002879172 @default.
- W1990692227 cites W2016843600 @default.
- W1990692227 cites W2022298723 @default.
- W1990692227 cites W2024428954 @default.
- W1990692227 cites W2031845501 @default.
- W1990692227 cites W2039543356 @default.
- W1990692227 cites W2046740640 @default.
- W1990692227 cites W2046849077 @default.
- W1990692227 cites W2057009086 @default.
- W1990692227 cites W2057642252 @default.
- W1990692227 cites W2059643240 @default.
- W1990692227 cites W2060440868 @default.
- W1990692227 cites W2061848121 @default.
- W1990692227 cites W2067708822 @default.
- W1990692227 cites W2075867600 @default.
- W1990692227 cites W2091321240 @default.
- W1990692227 cites W2091730954 @default.
- W1990692227 cites W2100041796 @default.
- W1990692227 cites W2106855576 @default.
- W1990692227 cites W2107711002 @default.
- W1990692227 cites W2114918609 @default.
- W1990692227 cites W2114930285 @default.
- W1990692227 cites W2116870926 @default.
- W1990692227 cites W2118087726 @default.
- W1990692227 cites W2125598794 @default.
- W1990692227 cites W2135527941 @default.
- W1990692227 cites W2164735889 @default.
- W1990692227 cites W2321202369 @default.
- W1990692227 cites W2334795095 @default.
- W1990692227 cites W2953127875 @default.
- W1990692227 doi "https://doi.org/10.1016/j.bmc.2013.12.020" @default.
- W1990692227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24398381" @default.
- W1990692227 hasPublicationYear "2014" @default.
- W1990692227 type Work @default.
- W1990692227 sameAs 1990692227 @default.
- W1990692227 citedByCount "24" @default.
- W1990692227 countsByYear W19906922272015 @default.
- W1990692227 countsByYear W19906922272016 @default.
- W1990692227 countsByYear W19906922272017 @default.
- W1990692227 countsByYear W19906922272019 @default.
- W1990692227 countsByYear W19906922272020 @default.
- W1990692227 countsByYear W19906922272021 @default.
- W1990692227 countsByYear W19906922272022 @default.
- W1990692227 countsByYear W19906922272023 @default.
- W1990692227 crossrefType "journal-article" @default.
- W1990692227 hasAuthorship W1990692227A5015862647 @default.
- W1990692227 hasAuthorship W1990692227A5021372943 @default.
- W1990692227 hasAuthorship W1990692227A5033881429 @default.
- W1990692227 hasAuthorship W1990692227A5038629290 @default.
- W1990692227 hasAuthorship W1990692227A5038956975 @default.
- W1990692227 hasAuthorship W1990692227A5039475493 @default.
- W1990692227 hasAuthorship W1990692227A5040902002 @default.
- W1990692227 hasAuthorship W1990692227A5042214848 @default.
- W1990692227 hasAuthorship W1990692227A5090002492 @default.
- W1990692227 hasBestOaLocation W19906922271 @default.
- W1990692227 hasConcept C114373084 @default.
- W1990692227 hasConcept C116073593 @default.
- W1990692227 hasConcept C136764020 @default.
- W1990692227 hasConcept C142724271 @default.
- W1990692227 hasConcept C161790260 @default.
- W1990692227 hasConcept C178790620 @default.
- W1990692227 hasConcept C185592680 @default.
- W1990692227 hasConcept C18616679 @default.
- W1990692227 hasConcept C202751555 @default.
- W1990692227 hasConcept C2777625466 @default.
- W1990692227 hasConcept C2779692420 @default.
- W1990692227 hasConcept C2781421772 @default.
- W1990692227 hasConcept C2911037157 @default.
- W1990692227 hasConcept C41008148 @default.
- W1990692227 hasConcept C55493867 @default.
- W1990692227 hasConcept C61156836 @default.
- W1990692227 hasConcept C71240020 @default.
- W1990692227 hasConcept C71924100 @default.
- W1990692227 hasConcept C71928629 @default.
- W1990692227 hasConcept C98274493 @default.
- W1990692227 hasConceptScore W1990692227C114373084 @default.
- W1990692227 hasConceptScore W1990692227C116073593 @default.
- W1990692227 hasConceptScore W1990692227C136764020 @default.