FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990698400> ?p ?o ?g. }

• W1990698400 endingPage "88" @default.
• W1990698400 startingPage "83" @default.
• W1990698400 abstract "The actions of estrogen (E) and progestogen (P) on normal endometrium are reviewed in order to give insight into endometrial hyperplasia and carcinoma. The entry of E from plasma may be protein-mediated. Human endometrium slices metabolize estradiol-17beta to an extent which varies with the stage of the cycle. Endometrium with cystic or anovulatory hyperplasia or adenocarcinoma behaves as proliferative endometrium. P in rats blocked E-induced replenishment of cytoplasmic receptors and caused a decrease in the quantity of cytoplasmic E receptors. Estrone and estriol had less affinity in binding to receptors than estradiol-17beta and this is important as a factor in the biological effect of these steroids. It has been noticed that the length of time the estrogen-receptor complex remains in the nucleus is a factor of critical importance for the biological potency as well. Weak estrogens may be as effective as estradiol-17beta if administered often enough. P enters the target cells through simple diffusion. Estradiol-17beta induces synthesis of new P uterine receptors while P itself seems to inactivate its own receptor. The role of E in the development of endometrial cancer is discussed. Results from a Swedish study suggest that prolonged estrogen stimulation unopposed by P can produce endometrial hyperplasia with a progression of changes leading to endometrial carcinoma. It is suggested that until the role of E in endometrial carcinoma is elucidated E should be administered only for established indications and only in a cyclical manner." @default.
• W1990698400 created "2016-06-24" @default.
• W1990698400 creator A5051668998 @default.
• W1990698400 date "1977-01-01" @default.
• W1990698400 modified "2023-09-23" @default.
• W1990698400 title "Endometrial Hyperplasia and Carcinoma: Histopathology and Hormonal Factors" @default.
• W1990698400 cites W1456855935 @default.
• W1990698400 cites W1487472049 @default.
• W1990698400 cites W1508400086 @default.
• W1990698400 cites W1515245060 @default.
• W1990698400 cites W1548046676 @default.
• W1990698400 cites W1601237744 @default.
• W1990698400 cites W182278069 @default.
• W1990698400 cites W1934466652 @default.
• W1990698400 cites W1966239078 @default.
• W1990698400 cites W1969985054 @default.
• W1990698400 cites W1973947446 @default.
• W1990698400 cites W1978601816 @default.
• W1990698400 cites W1982327222 @default.
• W1990698400 cites W1982804619 @default.
• W1990698400 cites W1985833456 @default.
• W1990698400 cites W1985881178 @default.
• W1990698400 cites W1985988917 @default.
• W1990698400 cites W1987218966 @default.
• W1990698400 cites W1992000777 @default.
• W1990698400 cites W2002462727 @default.
• W1990698400 cites W2008452386 @default.
• W1990698400 cites W2012345238 @default.
• W1990698400 cites W2013352780 @default.
• W1990698400 cites W2014706072 @default.
• W1990698400 cites W2019684061 @default.
• W1990698400 cites W2020655987 @default.
• W1990698400 cites W2022787906 @default.
• W1990698400 cites W2025614121 @default.
• W1990698400 cites W2033901424 @default.
• W1990698400 cites W2044312347 @default.
• W1990698400 cites W2050770488 @default.
• W1990698400 cites W2067209117 @default.
• W1990698400 cites W2076934848 @default.
• W1990698400 cites W2077857833 @default.
• W1990698400 cites W2083454223 @default.
• W1990698400 cites W2086780680 @default.
• W1990698400 cites W2095688405 @default.
• W1990698400 cites W2107382561 @default.
• W1990698400 cites W2145614616 @default.
• W1990698400 cites W2169555827 @default.
• W1990698400 cites W2188925218 @default.
• W1990698400 cites W2291314521 @default.
• W1990698400 cites W2298491915 @default.
• W1990698400 cites W2314604683 @default.
• W1990698400 cites W2321712742 @default.
• W1990698400 cites W2336212480 @default.
• W1990698400 cites W2401194347 @default.
• W1990698400 cites W2414823926 @default.
• W1990698400 cites W2425930994 @default.
• W1990698400 cites W2431478226 @default.
• W1990698400 cites W2434189854 @default.
• W1990698400 cites W2518068340 @default.
• W1990698400 cites W2252390583 @default.
• W1990698400 doi "https://doi.org/10.3109/00016347709156346" @default.
• W1990698400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/269629" @default.
• W1990698400 hasPublicationYear "1977" @default.
• W1990698400 type Work @default.
• W1990698400 sameAs 1990698400 @default.
• W1990698400 citedByCount "5" @default.
• W1990698400 crossrefType "journal-article" @default.
• W1990698400 hasAuthorship W1990698400A5051668998 @default.
• W1990698400 hasConcept C126322002 @default.
• W1990698400 hasConcept C142724271 @default.
• W1990698400 hasConcept C2777546739 @default.
• W1990698400 hasConcept C2777562237 @default.
• W1990698400 hasConcept C2777689261 @default.
• W1990698400 hasConcept C29456083 @default.
• W1990698400 hasConcept C42407357 @default.
• W1990698400 hasConcept C544855455 @default.
• W1990698400 hasConcept C71315377 @default.
• W1990698400 hasConcept C71924100 @default.
• W1990698400 hasConceptScore W1990698400C126322002 @default.
• W1990698400 hasConceptScore W1990698400C142724271 @default.
• W1990698400 hasConceptScore W1990698400C2777546739 @default.
• W1990698400 hasConceptScore W1990698400C2777562237 @default.
• W1990698400 hasConceptScore W1990698400C2777689261 @default.
• W1990698400 hasConceptScore W1990698400C29456083 @default.
• W1990698400 hasConceptScore W1990698400C42407357 @default.
• W1990698400 hasConceptScore W1990698400C544855455 @default.
• W1990698400 hasConceptScore W1990698400C71315377 @default.
• W1990698400 hasConceptScore W1990698400C71924100 @default.
• W1990698400 hasIssue "s65" @default.
• W1990698400 hasLocation W19906984001 @default.
• W1990698400 hasLocation W19906984002 @default.
• W1990698400 hasOpenAccess W1990698400 @default.
• W1990698400 hasPrimaryLocation W19906984001 @default.
• W1990698400 hasRelatedWork W1990698400 @default.
• W1990698400 hasRelatedWork W2011363925 @default.
• W1990698400 hasRelatedWork W2166172992 @default.
• W1990698400 hasRelatedWork W2379235935 @default.
• W1990698400 hasRelatedWork W2390466215 @default.
• W1990698400 hasRelatedWork W2397501214 @default.

• next