FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990726712> ?p ?o ?g. }

• W1990726712 endingPage "6289" @default.
• W1990726712 startingPage "6281" @default.
• W1990726712 abstract "ABSTRACT The cell-wall-less prokaryote Mycoplasma pneumoniae , long considered among the smallest and simplest cells capable of self-replication, has a distinct cellular polarity characterized by the presence of a differentiated terminal organelle which functions in adherence to human respiratory epithelium, gliding motility, and cell division. Characterization of hemadsorption (HA)-negative mutants has resulted in identification of several terminal organelle proteins, including P30, the loss of which results in developmental defects and decreased adherence to host cells, but their impact on M. pneumoniae gliding has not been investigated. Here we examined the contribution of P30 to gliding motility on the basis of satellite growth and cell gliding velocity and frequency. M. pneumoniae HA mutant II-3 lacking P30 was nonmotile, but HA mutant II-7 producing a truncated P30 was motile, albeit at a velocity 50-fold less than that of the wild type. HA-positive revertant II-3R producing an altered P30 was unexpectedly not fully wild type with respect to gliding. Complementation of mutant II-3 with recombinant wild-type and mutant alleles confirmed the correlation between gliding defect and loss or alteration in P30. Surprisingly, fusion of yellow fluorescent protein to the C terminus of P30 had little impact on cell gliding velocity and significantly enhanced HA. Finally, while quantitative examination of HA revealed clear distinctions among these mutant strains, gliding defects did not correlate strictly with the HA phenotype, and all strains attached to glass at wild-type levels. Taken together, these findings suggest a role for P30 in gliding motility that is distinct from its requirement in adherence." @default.
• W1990726712 created "2016-06-24" @default.
• W1990726712 creator A5010139321 @default.
• W1990726712 creator A5028899774 @default.
• W1990726712 creator A5050048639 @default.
• W1990726712 date "2005-09-15" @default.
• W1990726712 modified "2023-09-25" @default.
• W1990726712 title "Mutant Analysis Reveals a Specific Requirement for Protein P30 in<i>Mycoplasma pneumoniae</i>Gliding Motility" @default.
• W1990726712 cites W1493124379 @default.
• W1990726712 cites W1535754028 @default.
• W1990726712 cites W1542097161 @default.
• W1990726712 cites W1556991419 @default.
• W1990726712 cites W1590425268 @default.
• W1990726712 cites W1605902548 @default.
• W1990726712 cites W1608769716 @default.
• W1990726712 cites W1625173052 @default.
• W1990726712 cites W1627609927 @default.
• W1990726712 cites W1641704738 @default.
• W1990726712 cites W1672810485 @default.
• W1990726712 cites W1701458614 @default.
• W1990726712 cites W1844606485 @default.
• W1990726712 cites W1878059821 @default.
• W1990726712 cites W1918267335 @default.
• W1990726712 cites W1940536810 @default.
• W1990726712 cites W1946724236 @default.
• W1990726712 cites W1982075056 @default.
• W1990726712 cites W1986219422 @default.
• W1990726712 cites W1990909014 @default.
• W1990726712 cites W1994169274 @default.
• W1990726712 cites W2002821553 @default.
• W1990726712 cites W2010327531 @default.
• W1990726712 cites W2018289835 @default.
• W1990726712 cites W2034079466 @default.
• W1990726712 cites W2041652393 @default.
• W1990726712 cites W2050002986 @default.
• W1990726712 cites W2060413844 @default.
• W1990726712 cites W2070411677 @default.
• W1990726712 cites W2072167147 @default.
• W1990726712 cites W2076798542 @default.
• W1990726712 cites W2078825236 @default.
• W1990726712 cites W2095375976 @default.
• W1990726712 cites W2096718691 @default.
• W1990726712 cites W2100837269 @default.
• W1990726712 cites W2100948854 @default.
• W1990726712 cites W2101108802 @default.
• W1990726712 cites W2105978248 @default.
• W1990726712 cites W2106515994 @default.
• W1990726712 cites W2107663736 @default.
• W1990726712 cites W2108939871 @default.
• W1990726712 cites W2116762122 @default.
• W1990726712 cites W2123859786 @default.
• W1990726712 cites W2131941208 @default.
• W1990726712 cites W2133966658 @default.
• W1990726712 cites W2146250336 @default.
• W1990726712 cites W2147694156 @default.
• W1990726712 cites W2148341015 @default.
• W1990726712 cites W2148839944 @default.
• W1990726712 cites W2157847185 @default.
• W1990726712 cites W2158327469 @default.
• W1990726712 cites W2193699385 @default.
• W1990726712 cites W2328447565 @default.
• W1990726712 cites W2414257730 @default.
• W1990726712 cites W4206532155 @default.
• W1990726712 doi "https://doi.org/10.1128/jb.187.18.6281-6289.2005" @default.
• W1990726712 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1236621" @default.
• W1990726712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16159760" @default.
• W1990726712 hasPublicationYear "2005" @default.
• W1990726712 type Work @default.
• W1990726712 sameAs 1990726712 @default.
• W1990726712 citedByCount "51" @default.
• W1990726712 countsByYear W19907267122012 @default.
• W1990726712 countsByYear W19907267122014 @default.
• W1990726712 countsByYear W19907267122015 @default.
• W1990726712 countsByYear W19907267122016 @default.
• W1990726712 countsByYear W19907267122017 @default.
• W1990726712 countsByYear W19907267122018 @default.
• W1990726712 countsByYear W19907267122020 @default.
• W1990726712 countsByYear W19907267122021 @default.
• W1990726712 crossrefType "journal-article" @default.
• W1990726712 hasAuthorship W1990726712A5010139321 @default.
• W1990726712 hasAuthorship W1990726712A5028899774 @default.
• W1990726712 hasAuthorship W1990726712A5050048639 @default.
• W1990726712 hasBestOaLocation W19907267122 @default.
• W1990726712 hasConcept C104317684 @default.
• W1990726712 hasConcept C143065580 @default.
• W1990726712 hasConcept C1491633281 @default.
• W1990726712 hasConcept C166957645 @default.
• W1990726712 hasConcept C168240541 @default.
• W1990726712 hasConcept C188082640 @default.
• W1990726712 hasConcept C207583985 @default.
• W1990726712 hasConcept C2777914695 @default.
• W1990726712 hasConcept C2778838687 @default.
• W1990726712 hasConcept C2779215961 @default.
• W1990726712 hasConcept C54355233 @default.
• W1990726712 hasConcept C58207958 @default.
• W1990726712 hasConcept C64745115 @default.
• W1990726712 hasConcept C85813293 @default.
• W1990726712 hasConcept C86803240 @default.

• next