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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990733191> ?p ?o ?g. }

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• W1990733191 abstract "Starting from a benzazepine sulfonamide 5-HT(6) receptor antagonist lead with limited brain penetration, application of a strategy of conformational constraint and reduction of hydrogen bond donor count led to a novel series of tricyclic derivatives with high 5-HT(6) receptor affinity and excellent brain:blood ratios." @default.
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• W1990733191 date "2008-10-01" @default.
• W1990733191 modified "2023-10-12" @default.
• W1990733191 title "Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists" @default.
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• W1990733191 doi "https://doi.org/10.1016/j.bmcl.2008.08.010" @default.
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