FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990749761> ?p ?o ?g. }

• W1990749761 endingPage "226" @default.
• W1990749761 startingPage "219" @default.
• W1990749761 abstract "In order to investigate the involvement of the opioid and nociceptin/orphanin FQ (N/OFQ) system in alcohol drinking behaviour, N/OFQ and the opioid peptides dynorphin B (DYNB) and Met-enkephalin-Arg(6) Phe(7) (MEAP) were examined in the alcohol-preferring C57BL/6J mice. Basal peptide levels were compared in the brain and the pituitary gland with basal levels in the alcohol-avoiding DBA/2J mice. Furthermore, the effects of chronic alcohol self-administration on peptides were studied in the C57BL/6J mice. Compared to the DBA/2J mice, C57BL/6J mice had low immunoreactive (ir) levels of DYNB and MEAP in the nucleus accumbens, the hippocampus, and the substantia nigra, low ir-DYNB levels in the striatum and low ir-MEAP levels in the frontal cortex. Higher ir-DYNB levels in the pituitary gland and in the periaqueductal gray (PAG) and higher ir-N/OFQ levels in the frontal cortex and in the hippocampus were detected in C57BL/6J mice compared to the DBA/2J mice. After 4 weeks of voluntary alcohol consumption, only minor changes in steady-state peptide levels were identified. However, 5 days after the alcohol-drinking period, lower levels of all peptides were detected in the ventral tegmental area and ir-DYNB levels were also lower in the amygdala and in the substantia nigra. Twenty-one days after cessation of alcohol self-administration, the opioid peptides in alcohol-consuming C57BL/6J mice were lower in the PAG, the N/OFQ was lower in the frontal cortex and DYNB was higher in the amygdala and substantia nigra as compared to control C57BL/6J mice. This study demonstrates strain differences between C57BL/6J mice and DBA/2J mice that could contribute to divergent drug-taking behaviour, and it also demonstrates time- and structure-specific changes in neuropeptide levels after alcohol self-administration in the C57BL/6J mice." @default.
• W1990749761 created "2016-06-24" @default.
• W1990749761 creator A5000992112 @default.
• W1990749761 creator A5070074228 @default.
• W1990749761 creator A5081521018 @default.
• W1990749761 creator A5084829496 @default.
• W1990749761 date "2000-09-01" @default.
• W1990749761 modified "2023-10-16" @default.
• W1990749761 title "Basal levels and alcohol-induced changes in nociceptin/orphanin FQ, dynorphin, and enkephalin levels in C57BL/6J mice" @default.
• W1990749761 cites W1546812311 @default.
• W1990749761 cites W1782902465 @default.
• W1990749761 cites W1966157739 @default.
• W1990749761 cites W1974348633 @default.
• W1990749761 cites W1978462802 @default.
• W1990749761 cites W1980545520 @default.
• W1990749761 cites W1981727048 @default.
• W1990749761 cites W1997278612 @default.
• W1990749761 cites W2008106418 @default.
• W1990749761 cites W2008646949 @default.
• W1990749761 cites W2012659957 @default.
• W1990749761 cites W2015046028 @default.
• W1990749761 cites W2016562510 @default.
• W1990749761 cites W2018040121 @default.
• W1990749761 cites W2019991603 @default.
• W1990749761 cites W2023154106 @default.
• W1990749761 cites W2024493727 @default.
• W1990749761 cites W2025108780 @default.
• W1990749761 cites W2035911300 @default.
• W1990749761 cites W2037662305 @default.
• W1990749761 cites W2038749392 @default.
• W1990749761 cites W2040618359 @default.
• W1990749761 cites W2043136829 @default.
• W1990749761 cites W2046135515 @default.
• W1990749761 cites W2046563652 @default.
• W1990749761 cites W2050983933 @default.
• W1990749761 cites W2051455839 @default.
• W1990749761 cites W2055873049 @default.
• W1990749761 cites W2056401590 @default.
• W1990749761 cites W2057391423 @default.
• W1990749761 cites W2058186657 @default.
• W1990749761 cites W2058611932 @default.
• W1990749761 cites W2060738890 @default.
• W1990749761 cites W2066624199 @default.
• W1990749761 cites W2071553034 @default.
• W1990749761 cites W2072830432 @default.
• W1990749761 cites W2074115024 @default.
• W1990749761 cites W2081080615 @default.
• W1990749761 cites W2093559862 @default.
• W1990749761 cites W2104538950 @default.
• W1990749761 cites W2125536184 @default.
• W1990749761 cites W2133672910 @default.
• W1990749761 cites W2140629150 @default.
• W1990749761 cites W2162688555 @default.
• W1990749761 cites W2165398609 @default.
• W1990749761 cites W3161769974 @default.
• W1990749761 cites W4235095349 @default.
• W1990749761 doi "https://doi.org/10.1016/s0361-9230(00)00328-2" @default.
• W1990749761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11044599" @default.
• W1990749761 hasPublicationYear "2000" @default.
• W1990749761 type Work @default.
• W1990749761 sameAs 1990749761 @default.
• W1990749761 citedByCount "65" @default.
• W1990749761 countsByYear W19907497612012 @default.
• W1990749761 countsByYear W19907497612013 @default.
• W1990749761 countsByYear W19907497612014 @default.
• W1990749761 countsByYear W19907497612016 @default.
• W1990749761 countsByYear W19907497612017 @default.
• W1990749761 countsByYear W19907497612018 @default.
• W1990749761 countsByYear W19907497612020 @default.
• W1990749761 countsByYear W19907497612021 @default.
• W1990749761 countsByYear W19907497612022 @default.
• W1990749761 countsByYear W19907497612023 @default.
• W1990749761 crossrefType "journal-article" @default.
• W1990749761 hasAuthorship W1990749761A5000992112 @default.
• W1990749761 hasAuthorship W1990749761A5070074228 @default.
• W1990749761 hasAuthorship W1990749761A5081521018 @default.
• W1990749761 hasAuthorship W1990749761A5084829496 @default.
• W1990749761 hasConcept C118303440 @default.
• W1990749761 hasConcept C125439840 @default.
• W1990749761 hasConcept C126322002 @default.
• W1990749761 hasConcept C134018914 @default.
• W1990749761 hasConcept C137183658 @default.
• W1990749761 hasConcept C151077648 @default.
• W1990749761 hasConcept C170493617 @default.
• W1990749761 hasConcept C185592680 @default.
• W1990749761 hasConcept C2776552330 @default.
• W1990749761 hasConcept C2777803847 @default.
• W1990749761 hasConcept C2780062018 @default.
• W1990749761 hasConcept C2780938664 @default.
• W1990749761 hasConcept C2780948874 @default.
• W1990749761 hasConcept C2781063702 @default.
• W1990749761 hasConcept C513476851 @default.
• W1990749761 hasConcept C71924100 @default.
• W1990749761 hasConcept C88016717 @default.
• W1990749761 hasConceptScore W1990749761C118303440 @default.
• W1990749761 hasConceptScore W1990749761C125439840 @default.
• W1990749761 hasConceptScore W1990749761C126322002 @default.
• W1990749761 hasConceptScore W1990749761C134018914 @default.

• next