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• W1990755756 abstract "Stimulation of isolated rat Kupffer cells by viable Leptospira interrogans, Treponema pallidum and Borrelia garinii elicited cellular responses resulting in the release of different tumor necrosis factor α (TNF-α) levels, depending on the spirochetes. L. interrogans induced TNF-α levels higher than those achieved with B. garinii and T. pallidum (in this order), but lower than the levels achieved with lipopolysaccharide (LPS). In contrast to L. interrogans, pretreatment of borreliae and treponemes with polymyxin B did not substantially diminish the ability of B. garinii and T. pallidum to stimulate Kupffer cells. Purified T. pallidum lipoproteins TpN47, TmpA, TpN15–TpN17, and B. garinii OspA induced TNF-α responses comparable to that achieved by LPS. This response was almost insensitive to the action of polymyxin B." @default.
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• W1990755756 date "2004-04-01" @default.
• W1990755756 modified "2023-10-14" @default.
• W1990755756 title "Production of tumor necrosis factor α by<i>Treponema pallidum</i>,<i>Borrelia burgdorferi</i>s.l., and<i>Leptospira interrogans</i>in isolated rat Kupffer cells" @default.
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• W1990755756 doi "https://doi.org/10.1016/s0928-8244(03)00345-6" @default.
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