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- W1990775393 abstract "Resting mouse B lymphocytes were stimulated in vitro with Upopoiysaccharide, Sepharose‐coupled anti‐γ antibodies or a combination of the two. B lymphocytes stimulated with anti‐γ entered the cell‐cycle with more rapid kinetics and at a higher frequency than did the corresponding cell population stimulated with lipopolysaccharide. Using cell cycle analysis after DNA staining combined with an M phase block, the cell‐cycle kinetics of in vitro cultured B‐lymphocytes was studied. The labelling index of lipopoly saccharide stimulated B lymphocytes was 60% while that for anti‐γ Sepharose stimulated cells was 85%. The generation time of the actively cycling population from both types of cultures was constant and was of the order of 18 h. Thus, the fraction of B lymphocytes induced to proliferate in vitro varies depending on the stimulus, while the growth kinetics of the actively proliferating populations are remarkably constant." @default.
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- W1990775393 date "1995-01-01" @default.
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- W1990775393 title "Cell-Cycle Kinetics of Proliferating Mouse B Lymphocytes In Vitro" @default.
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- W1990775393 doi "https://doi.org/10.1111/j.1365-3083.1995.tb03539.x" @default.
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