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- W1990776064 abstract "Macrophages play a key role in several critical aspects of HIV disease. They appear to be the first cells infected by HIV and perhaps the very source of HIV production when CD4+ cells are markedly depleted in the patient. Macrophages and microglial cells are the cells infected by HIV in the CNS. In tonsils and adenoids of HIV-infected patients, macrophages fuse into multinucleated giant cells that produce copious amounts of virus. Finally, opportunistic pathogens can cause an upregulation of HIV production by macrophages, often in the multinucleated form." @default.
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- W1990776064 date "2001-01-01" @default.
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- W1990776064 title "The Macrophage in HIV Infection" @default.
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- W1990776064 doi "https://doi.org/10.1078/0171-2985-00098" @default.
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