Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990785341> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1990785341 endingPage "2046" @default.
- W1990785341 startingPage "2040" @default.
- W1990785341 abstract "Fulminant hepatitis is associated with apoptosis of hepatocytes, which is mediated via Fas and tumor necrosis factor (TNF) receptors. The clinical significance of apoptotic factors and these receptors was investigated in fulminant hepatitis.Serum levels of TNF-alpha, soluble TNF receptor-I and -II, soluble Fas antigen, and Fas ligand were measured. Then, the relationships between these parameters and the severity or prognosis of fulminant hepatitis were studied.Serum levels of TNF-alpha, soluble TNF receptor-I, and soluble TNF receptor-II were increased in acute-type fulminant hepatitis. In particular, soluble TNF receptor-I was significantly higher than in patients with subacute-type fulminant hepatitis, severe acute hepatitis, acute hepatitis, or healthy controls. The soluble TNF receptor-I level continued to increase or remained high in patients who died of acute-type fulminant hepatitis, and eight of nine patients had a level >10 ng/ml. In contrast, the soluble TNF receptor-I level remained <10 ng/ml in survivors. Soluble Fas and soluble Fas ligand levels tended to increase in all types of acute liver disease and were not specific to fulminant hepatitis.Our findings suggested that monitoring the soluble TNF receptor-I level may help to assess the prognosis of acute-type fulminant hepatitis and that TNF might be associated with massive hepatic necrosis." @default.
- W1990785341 created "2016-06-24" @default.
- W1990785341 creator A5025469685 @default.
- W1990785341 creator A5033544033 @default.
- W1990785341 creator A5038611892 @default.
- W1990785341 creator A5048560115 @default.
- W1990785341 creator A5051185122 @default.
- W1990785341 creator A5055210740 @default.
- W1990785341 date "2000-08-01" @default.
- W1990785341 modified "2023-09-26" @default.
- W1990785341 title "Significance of soluble TNF receptor-I in acute-type fulminant hepatitis" @default.
- W1990785341 cites W1497061219 @default.
- W1990785341 cites W1555794415 @default.
- W1990785341 cites W1577494663 @default.
- W1990785341 cites W1608215573 @default.
- W1990785341 cites W1888783223 @default.
- W1990785341 cites W1894649804 @default.
- W1990785341 cites W1975336660 @default.
- W1990785341 cites W2008779414 @default.
- W1990785341 cites W2010255267 @default.
- W1990785341 cites W2017472765 @default.
- W1990785341 cites W2031051797 @default.
- W1990785341 cites W2033873130 @default.
- W1990785341 cites W2040944339 @default.
- W1990785341 cites W2042796093 @default.
- W1990785341 cites W2048656662 @default.
- W1990785341 cites W2067534266 @default.
- W1990785341 cites W2071585015 @default.
- W1990785341 cites W2077212706 @default.
- W1990785341 cites W2082575834 @default.
- W1990785341 cites W2097880977 @default.
- W1990785341 cites W2115050900 @default.
- W1990785341 cites W2117637609 @default.
- W1990785341 cites W2147700544 @default.
- W1990785341 cites W2168945225 @default.
- W1990785341 cites W4232731515 @default.
- W1990785341 cites W4238904596 @default.
- W1990785341 cites W631146119 @default.
- W1990785341 cites W95884546 @default.
- W1990785341 doi "https://doi.org/10.1111/j.1572-0241.2000.02270.x" @default.
- W1990785341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10950055" @default.
- W1990785341 hasPublicationYear "2000" @default.
- W1990785341 type Work @default.
- W1990785341 sameAs 1990785341 @default.
- W1990785341 citedByCount "48" @default.
- W1990785341 countsByYear W19907853412012 @default.
- W1990785341 countsByYear W19907853412013 @default.
- W1990785341 countsByYear W19907853412014 @default.
- W1990785341 countsByYear W19907853412015 @default.
- W1990785341 countsByYear W19907853412017 @default.
- W1990785341 countsByYear W19907853412019 @default.
- W1990785341 crossrefType "journal-article" @default.
- W1990785341 hasAuthorship W1990785341A5025469685 @default.
- W1990785341 hasAuthorship W1990785341A5033544033 @default.
- W1990785341 hasAuthorship W1990785341A5038611892 @default.
- W1990785341 hasAuthorship W1990785341A5048560115 @default.
- W1990785341 hasAuthorship W1990785341A5051185122 @default.
- W1990785341 hasAuthorship W1990785341A5055210740 @default.
- W1990785341 hasConcept C126322002 @default.
- W1990785341 hasConcept C134018914 @default.
- W1990785341 hasConcept C170493617 @default.
- W1990785341 hasConcept C17991360 @default.
- W1990785341 hasConcept C203014093 @default.
- W1990785341 hasConcept C2776029263 @default.
- W1990785341 hasConcept C2781107259 @default.
- W1990785341 hasConcept C2994395758 @default.
- W1990785341 hasConcept C71924100 @default.
- W1990785341 hasConcept C90924648 @default.
- W1990785341 hasConceptScore W1990785341C126322002 @default.
- W1990785341 hasConceptScore W1990785341C134018914 @default.
- W1990785341 hasConceptScore W1990785341C170493617 @default.
- W1990785341 hasConceptScore W1990785341C17991360 @default.
- W1990785341 hasConceptScore W1990785341C203014093 @default.
- W1990785341 hasConceptScore W1990785341C2776029263 @default.
- W1990785341 hasConceptScore W1990785341C2781107259 @default.
- W1990785341 hasConceptScore W1990785341C2994395758 @default.
- W1990785341 hasConceptScore W1990785341C71924100 @default.
- W1990785341 hasConceptScore W1990785341C90924648 @default.
- W1990785341 hasIssue "8" @default.
- W1990785341 hasLocation W19907853411 @default.
- W1990785341 hasLocation W19907853412 @default.
- W1990785341 hasOpenAccess W1990785341 @default.
- W1990785341 hasPrimaryLocation W19907853411 @default.
- W1990785341 hasRelatedWork W1990717759 @default.
- W1990785341 hasRelatedWork W1996846474 @default.
- W1990785341 hasRelatedWork W2018368842 @default.
- W1990785341 hasRelatedWork W2033472167 @default.
- W1990785341 hasRelatedWork W2034583712 @default.
- W1990785341 hasRelatedWork W2052453588 @default.
- W1990785341 hasRelatedWork W2061429094 @default.
- W1990785341 hasRelatedWork W2063619316 @default.
- W1990785341 hasRelatedWork W2169225653 @default.
- W1990785341 hasRelatedWork W2414846389 @default.
- W1990785341 hasVolume "95" @default.
- W1990785341 isParatext "false" @default.
- W1990785341 isRetracted "false" @default.
- W1990785341 magId "1990785341" @default.
- W1990785341 workType "article" @default.