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- W1990795763 abstract "This chapter discusses the role of isozymes in metabolism. Isozymes are the multiple forms of enzymes catalyzing the same reaction in the same cell or organism. If several forms of the same enzymic activity exist, they perform a function in a distinct manner, and the difference is not the product of the reaction. The difference must then reside in the manner in which the product is formed. In fact, the components of some isozymic systems have been shown to differ, inter alia, in their affinity for substrates or cofactors, substrate or cofactor specificities, response to allosteric effectors, subcellular localization, susceptibility to dietary and/or hormonal treatments, or time of appearance during differentiation. This chapter discusses the involvement of isozymes in metabolic regulation and the role of compartmentation in metabolic regulation. A hypothetical model of metabolism and polyisozymic complexes in glucose utilization are also described in the chapter." @default.
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- W1990795763 date "1961-01-01" @default.
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- W1990795763 title "Effect of glutamic acid on the formation of two glutamic acid dehydrogenases of neurospora" @default.
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- W1990795763 doi "https://doi.org/10.1016/0006-291x(62)90364-9" @default.
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