Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990804731> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W1990804731 endingPage "21" @default.
- W1990804731 startingPage "21" @default.
- W1990804731 abstract "Recent literature has suggested that completion axillary lymph node dissection (ALND) in breast carcinoma patients with positive SLN may not be necessary. However, a method for determining the risk of non-SLN or extranodal disease remains to be established.To determine if pathological variables from primary tumors and sentinel lymph node (SLN) metastases could predict the probability of non-sentinel lymph node (NSLN) metastases and extranodal disease in patients with breast carcinoma and SLN metastases.84 women with T1-3 breast cancer and clinically-negative axillae underwent completion ALND. Maximum diameter and width of SLN metastases were measured to calculate metastatic area. When multiple SLNs contained metastases, areas were summed to calculate the Total Metastatic Area (TMA). Multiple linear regression models were used to identify predictive factors.Her-2/neu over-expression increased the odds of NSLN metastases (OR 4.3, p = 0.01) and extranodal disease (OR 7.9, p < 0.001). Independent SLN predictors were ≥1 positive SLN (OR, 7.35), maximum diameter and area of SLN metastases (OR 2.26, 1.85 respectively) and TMA (OR, 2.12). Maximum metastatic diameter/SLN diameter (OR 3.71, p = 0.04) and the area of metastases/SLN area (OR 3.4, p = 0.04) were predictive. For every 1 mm increase in diameter of SLN metastases, the odds of NSLN extranodal disease increased by 8.5% (p = 0.02). TMA >0.40 cm2 was an independent predictor for NSLN metastases and extranodal disease.Her-2/neu over-expression and parameters assessing metastatic burden in the SLN, particularly TMA, predicted the presence of NSLN involvement and extranodal disease in patients with breast carcinoma and SLN metastases." @default.
- W1990804731 created "2016-06-24" @default.
- W1990804731 creator A5021579919 @default.
- W1990804731 creator A5062242884 @default.
- W1990804731 creator A5078803755 @default.
- W1990804731 creator A5081815846 @default.
- W1990804731 date "2007-09-01" @default.
- W1990804731 modified "2023-09-27" @default.
- W1990804731 title "O-67 Prediction of axillary lymph node metastasis by size and grade of tumour an aid for the discussion of axillary surgery in patients with operable breast cancer" @default.
- W1990804731 doi "https://doi.org/10.1016/s1359-6349(07)71757-3" @default.
- W1990804731 hasPublicationYear "2007" @default.
- W1990804731 type Work @default.
- W1990804731 sameAs 1990804731 @default.
- W1990804731 citedByCount "1" @default.
- W1990804731 crossrefType "journal-article" @default.
- W1990804731 hasAuthorship W1990804731A5021579919 @default.
- W1990804731 hasAuthorship W1990804731A5062242884 @default.
- W1990804731 hasAuthorship W1990804731A5078803755 @default.
- W1990804731 hasAuthorship W1990804731A5081815846 @default.
- W1990804731 hasConcept C121608353 @default.
- W1990804731 hasConcept C126322002 @default.
- W1990804731 hasConcept C126838900 @default.
- W1990804731 hasConcept C142724271 @default.
- W1990804731 hasConcept C143998085 @default.
- W1990804731 hasConcept C2779013556 @default.
- W1990804731 hasConcept C2779720271 @default.
- W1990804731 hasConcept C2780212769 @default.
- W1990804731 hasConcept C2780849966 @default.
- W1990804731 hasConcept C2908949552 @default.
- W1990804731 hasConcept C2910278093 @default.
- W1990804731 hasConcept C3018521938 @default.
- W1990804731 hasConcept C530470458 @default.
- W1990804731 hasConcept C71924100 @default.
- W1990804731 hasConceptScore W1990804731C121608353 @default.
- W1990804731 hasConceptScore W1990804731C126322002 @default.
- W1990804731 hasConceptScore W1990804731C126838900 @default.
- W1990804731 hasConceptScore W1990804731C142724271 @default.
- W1990804731 hasConceptScore W1990804731C143998085 @default.
- W1990804731 hasConceptScore W1990804731C2779013556 @default.
- W1990804731 hasConceptScore W1990804731C2779720271 @default.
- W1990804731 hasConceptScore W1990804731C2780212769 @default.
- W1990804731 hasConceptScore W1990804731C2780849966 @default.
- W1990804731 hasConceptScore W1990804731C2908949552 @default.
- W1990804731 hasConceptScore W1990804731C2910278093 @default.
- W1990804731 hasConceptScore W1990804731C3018521938 @default.
- W1990804731 hasConceptScore W1990804731C530470458 @default.
- W1990804731 hasConceptScore W1990804731C71924100 @default.
- W1990804731 hasIssue "3" @default.
- W1990804731 hasLocation W19908047311 @default.
- W1990804731 hasOpenAccess W1990804731 @default.
- W1990804731 hasPrimaryLocation W19908047311 @default.
- W1990804731 hasRelatedWork W2012243297 @default.
- W1990804731 hasRelatedWork W2033699506 @default.
- W1990804731 hasRelatedWork W2054013891 @default.
- W1990804731 hasRelatedWork W2065749544 @default.
- W1990804731 hasRelatedWork W2069322701 @default.
- W1990804731 hasRelatedWork W2088112532 @default.
- W1990804731 hasRelatedWork W2341267087 @default.
- W1990804731 hasRelatedWork W2410397614 @default.
- W1990804731 hasRelatedWork W3009152082 @default.
- W1990804731 hasRelatedWork W3130634424 @default.
- W1990804731 hasVolume "5" @default.
- W1990804731 isParatext "false" @default.
- W1990804731 isRetracted "false" @default.
- W1990804731 magId "1990804731" @default.
- W1990804731 workType "article" @default.