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- W1990808230 abstract "The distinction between exudates and transudates is very important in the patient management. Here we evaluate whether the acute-phase protein serum amyloid A (SAA), in comparison with C reactive protein (CRP) and total protein (TP), can be useful in this discrimination. CRP, SAA, and TP were determined in 36 exudate samples (27 pleural and 9 ascitic) and in 12 transudates (9 pleural and 3 ascitic). CRP, SAA, and TP were measured. SAA present in the exudate corresponded to<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML alttext=$10%$ id=E1><mml:mn>10</mml:mn><mml:mi>%</mml:mi></mml:math>of the amount found in serum, that is, the exudate/serum ratio (E/S) was<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML alttext=$0.10pm 0.13$ id=E2><mml:mn>0.10</mml:mn><mml:mo>±</mml:mo><mml:mn>0.13</mml:mn></mml:math>. For comparison, the exudate/serum ratio for CRP and TP was<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML alttext=$0.39pm 0.37$ id=E3><mml:mn>0.39</mml:mn><mml:mo>±</mml:mo><mml:mn>0.37</mml:mn></mml:math>and<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML alttext=$0.68pm 0.15$ id=E4><mml:mn>0.68</mml:mn><mml:mo>±</mml:mo><mml:mn>0.15</mml:mn></mml:math>, respectively. There was a strong positive correlation between serum and exudate SAA concentration (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML alttext=$r=$,$0.764; p/lt$,$0.0001$ id=E5><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn>0.764</mml:mn><mml:mo>;</mml:mo><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.0001</mml:mn></mml:math>). The concentration of SAA in transudates was low and did not overlap with that found in exudates (0.02-0.21 versus 0.8–360.5 g/mL). SAA in pleural and ascitic exudates results mainly from leakage of the serum protein via the inflamed membrane. A comparison of the E/S ratio of SAA and CRP points SAA as a very good marker in discriminating between exudates and transudates" @default.
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- W1990808230 date "2006-01-01" @default.
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- W1990808230 title "The Acute-Phase Proteins Serum Amyloid A and C Reactive Protein in Transudates and Exudates" @default.
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- W1990808230 doi "https://doi.org/10.1155/mi/2006/47297" @default.
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