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- W1990808519 abstract "1663 Oxygen consumption during incremental exercise (IE) follows a biphasic response including an early and late linear phase. Chronic lung disorders (CLD) such as Cystic Fibrosis or Asthma are associated with decreased exercise tolerance compared to Controls (CN). Examining the biphasic response during IE in children with CLD has not been evaluated. Thirty six subjects with CLD (mean 10.6, range 7-17 yrs) and 14 CN (11.0, 7-16 yrs) completed an IE test to exhaustion with VO2 data recorded every 5 seconds. (Table)TableThe CLD group showed a delayed increase in VO2 consumption with a reduced early phase slope (7.1 ± 4.0 l/min/sec vs 10.7 ± 6.4, p<.02). Late phase increases in VO2 consumption did not differ between CLD and CN (slope: 3.05 ± 2.2 l/min/sec vs 2.65 ± 3.3, p=NS). This compromised early phase response in CLD may be attributed to increases in dead space ventilation that must be overcome early in the initiation of exercise. As increased dead space ventilation is overcome in the CLD group, exercise proceeds in a similar fashion to the CN group with no differences seen in late phase response." @default.
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- W1990808519 date "1999-05-01" @default.
- W1990808519 modified "2023-09-26" @default.
- W1990808519 title "BIPHASIC RESPONSES TO EXERCISE APPEAR COMPROMISED IN CHILDREN WITH CHRONIC PULMONARY DISORDERS" @default.
- W1990808519 doi "https://doi.org/10.1097/00005768-199905001-01659" @default.
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