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- W1990824093 abstract "HomeCirculationVol. 104, No. 22Visualization of Tissue Prolapse Between Coronary Stent Struts by Optical Coherence Tomography Free AccessOtherPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessOtherPDF/EPUBVisualization of Tissue Prolapse Between Coronary Stent Struts by Optical Coherence TomographyComparison With Intravascular Ultrasound Ik-Kyung Jang, Guillermo Tearney and Brett Bouma Ik-Kyung JangIk-Kyung Jang From Massachusetts General Hospital, Harvard Medical School, Boston, Mass. Search for more papers by this author , Guillermo TearneyGuillermo Tearney From Massachusetts General Hospital, Harvard Medical School, Boston, Mass. Search for more papers by this author and Brett BoumaBrett Bouma From Massachusetts General Hospital, Harvard Medical School, Boston, Mass. Search for more papers by this author Originally published27 Nov 2001https://doi.org/10.1161/hc4701.098069Circulation. 2001;104:2754A 65-year-old man underwent cardiac catheterization for unstable angina pectoris. The coronary angiogram revealed a significant stenosis of the right coronary artery, which was treated with a 3.0×16 mm NIR stent. A postintervention coronary angiogram showed excellent results, and intravascular ultrasound (IVUS; 30 MHz, Ultracross, Boston Scientific) showed a well-deployed stent (Figure, A). A 3.2 F optical coherence tomography (OCT) catheter, advanced to the same site, showed well-apposed stent struts (Figure, B). In addition, tissue prolapse between the stent struts (12 to 3 o’clock in B) was clearly visualized. The tissue prolapse occurred mainly in an area with a lower OCT signal intensity (vessel wall visualized between the stent struts), which is suggestive of a plaque with decreased collagen content. A retrospective review of the IVUS study showed an area of possible tissue prolapse at the corresponding location (1 o’clock in A). Download figureDownload PowerPointIVUS (A) and OCT (B) images of the stented right coronary artery are shown. Although IVUS showed a well-deployed stent, the detailed structure around the stent struts is not well visualized. In addition, OCT clearly visualized tissue prolapse between the stent struts (12 to 3 o’clock). The tissue prolapse occurred mainly in an area with lower OCT signal intensity, which is suggestive of a plaque with a large lipid content.OCT is an optical analog of IVUS with a high resolution (10 μm versus 100 μm of IVUS). Recently, our laboratory developed a catheter-based intracoronary OCT system. The OCT image(Figure, B) was acquired during the first application of this technology in humans. This new imaging modality may be useful in improving the outcome of coronary intervention and may also help identify vulnerable coronary plaques.The editor of Images in Cardiovascular Medicine is Hugh A. McAllister, Jr, MD, Chief, Department of Pathology, St. Luke's Episcopal Hospital and Texas Heart Institute, and Clinical Professor of Pathology, University of Texas Medical School and Baylor College of Medicine.Circulation encourages readers to submit cardiovascular images to the Circulation Editorial Office, St. Luke’s Episcopal Hospital/Texas Heart Institute, 6720 Bertner Ave, MC1-267, Houston, TX 77030.FootnotesCorrespondence to Ik-Kyung Jang, MD, Cardiology Division, Bulfinch 105, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114. E-mail [email protected] eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsCited By Viscusi M, La Porta Y, Migliaro G, Gargano G, Nusca A, Gatto L, Budassi S, Paolucci L, Mangiacapra F, Ricottini E, Melfi R, Rinaldi R, Prati F, Ussia G and Grigioni F (2023) Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance, Photonics, 10.3390/photonics10020158, 10:2, (158) Bouma B, de Boer J, Huang D, Jang I, Yonetsu T, Leggett C, Leitgeb R, Sampson D, Suter M, Vakoc B, Villiger M and Wojtkowski M (2022) Optical coherence tomography, Nature Reviews Methods Primers, 10.1038/s43586-022-00162-2, 2:1 Wang T, Pfeiffer T, Akyildiz A, van Beusekom H, Huber R, van der Steen A and van Soest G (2022) Intravascular optical coherence elastography, Biomedical Optics Express, 10.1364/BOE.470039, 13:10, (5418), Online publication date: 1-Oct-2022. 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