FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990949826> ?p ?o ?g. }

• W1990949826 endingPage "389" @default.
• W1990949826 startingPage "379" @default.
• W1990949826 abstract "Two types of spontaneous interictal discharge, identified as fast and slow events, can be recorded from the hippocampal CA3 area in rat brain slices during application of 4-aminopyridine (4AP) (50 μm). Here, we addressed how neurosteroids modulate the occurrence of these interictal events and of the associated high-frequency oscillations (HFOs) (ripples, 80–200 Hz; fast ripples, 250–500 Hz). Under control conditions (i.e. during 4AP application), ripples and fast ripples were detected in 12.3 and 17.5% of fast events, respectively; in contrast, the majority of slow events (> 98%) did not co-occur with HFOs. Application of 0.1, 1 or 5 μm allotetrahydrodeoxycorticosterone (THDOC) to 4AP-treated slices caused a dose-dependent decrease in the duration of the fast events and an increase in the occurrence of ripples, but not fast ripples; in contrast, the duration of slow events increased. THDOC potentiated the slow events that were recorded during pharmacological blockade of glutamatergic transmission, but had no effect on interictal discharges occurring during GABAA receptor antagonism. These results demonstrate that potentiation of GABAA receptor-mediated signaling by THDOC differentially affects slow and fast interictal discharges; these differences may provide insights into how hyperexcitable activity is influenced by neurosteroids." @default.
• W1990949826 created "2016-06-24" @default.
• W1990949826 creator A5041039066 @default.
• W1990949826 creator A5066470294 @default.
• W1990949826 date "2014-12-04" @default.
• W1990949826 modified "2023-09-29" @default.
• W1990949826 title "Neurosteroids differentially modulate fast and slow interictal discharges in the hippocampal CA3 area" @default.
• W1990949826 cites W1504576116 @default.
• W1990949826 cites W1519218320 @default.
• W1990949826 cites W1623815617 @default.
• W1990949826 cites W1819857017 @default.
• W1990949826 cites W1955575446 @default.
• W1990949826 cites W1976707885 @default.
• W1990949826 cites W1980716364 @default.
• W1990949826 cites W1987834694 @default.
• W1990949826 cites W1989710398 @default.
• W1990949826 cites W1990627393 @default.
• W1990949826 cites W1994288348 @default.
• W1990949826 cites W1997629662 @default.
• W1990949826 cites W2003548320 @default.
• W1990949826 cites W2005811850 @default.
• W1990949826 cites W2007352211 @default.
• W1990949826 cites W2008871773 @default.
• W1990949826 cites W2009332732 @default.
• W1990949826 cites W2011267914 @default.
• W1990949826 cites W2016321438 @default.
• W1990949826 cites W2017227716 @default.
• W1990949826 cites W2023133270 @default.
• W1990949826 cites W2038652907 @default.
• W1990949826 cites W2050990654 @default.
• W1990949826 cites W2052597020 @default.
• W1990949826 cites W2059915602 @default.
• W1990949826 cites W2060019069 @default.
• W1990949826 cites W2079103153 @default.
• W1990949826 cites W2080721208 @default.
• W1990949826 cites W2091060078 @default.
• W1990949826 cites W2125616660 @default.
• W1990949826 cites W2135913462 @default.
• W1990949826 cites W2137591123 @default.
• W1990949826 cites W2170088360 @default.
• W1990949826 cites W2222396702 @default.
• W1990949826 cites W2227856689 @default.
• W1990949826 cites W2430458944 @default.
• W1990949826 cites W2461402597 @default.
• W1990949826 cites W4256048563 @default.
• W1990949826 cites W4322701228 @default.
• W1990949826 doi "https://doi.org/10.1111/ejn.12797" @default.
• W1990949826 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4880482" @default.
• W1990949826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25471484" @default.
• W1990949826 hasPublicationYear "2014" @default.
• W1990949826 type Work @default.
• W1990949826 sameAs 1990949826 @default.
• W1990949826 citedByCount "3" @default.
• W1990949826 countsByYear W19909498262015 @default.
• W1990949826 countsByYear W19909498262017 @default.
• W1990949826 countsByYear W19909498262020 @default.
• W1990949826 crossrefType "journal-article" @default.
• W1990949826 hasAuthorship W1990949826A5041039066 @default.
• W1990949826 hasAuthorship W1990949826A5066470294 @default.
• W1990949826 hasBestOaLocation W19909498262 @default.
• W1990949826 hasConcept C126322002 @default.
• W1990949826 hasConcept C148762608 @default.
• W1990949826 hasConcept C168258287 @default.
• W1990949826 hasConcept C169760540 @default.
• W1990949826 hasConcept C170493617 @default.
• W1990949826 hasConcept C17755696 @default.
• W1990949826 hasConcept C185592680 @default.
• W1990949826 hasConcept C200170125 @default.
• W1990949826 hasConcept C25274449 @default.
• W1990949826 hasConcept C2780648746 @default.
• W1990949826 hasConcept C2780715579 @default.
• W1990949826 hasConcept C2781161787 @default.
• W1990949826 hasConcept C44796713 @default.
• W1990949826 hasConcept C522805319 @default.
• W1990949826 hasConcept C61174792 @default.
• W1990949826 hasConcept C71924100 @default.
• W1990949826 hasConcept C86803240 @default.
• W1990949826 hasConceptScore W1990949826C126322002 @default.
• W1990949826 hasConceptScore W1990949826C148762608 @default.
• W1990949826 hasConceptScore W1990949826C168258287 @default.
• W1990949826 hasConceptScore W1990949826C169760540 @default.
• W1990949826 hasConceptScore W1990949826C170493617 @default.
• W1990949826 hasConceptScore W1990949826C17755696 @default.
• W1990949826 hasConceptScore W1990949826C185592680 @default.
• W1990949826 hasConceptScore W1990949826C200170125 @default.
• W1990949826 hasConceptScore W1990949826C25274449 @default.
• W1990949826 hasConceptScore W1990949826C2780648746 @default.
• W1990949826 hasConceptScore W1990949826C2780715579 @default.
• W1990949826 hasConceptScore W1990949826C2781161787 @default.
• W1990949826 hasConceptScore W1990949826C44796713 @default.
• W1990949826 hasConceptScore W1990949826C522805319 @default.
• W1990949826 hasConceptScore W1990949826C61174792 @default.
• W1990949826 hasConceptScore W1990949826C71924100 @default.
• W1990949826 hasConceptScore W1990949826C86803240 @default.
• W1990949826 hasFunder F4320319909 @default.
• W1990949826 hasFunder F4320334506 @default.
• W1990949826 hasIssue "3" @default.
• W1990949826 hasLocation W19909498261 @default.

• next