Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990991109> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1990991109 endingPage "30" @default.
- W1990991109 startingPage "26" @default.
- W1990991109 abstract "Intravenous injection of lyophilized whole cells of various oral streptococcal strains into muramyldipeptide (MDP)-primed C3H/HeN mice induces rapid anaphylactoid shock. Here we examined the mechanism underlying this shock. In non-primed mice, Streptococcus intermedius K-213K (SiK213) and Streptococcus constellatus T21 (ScT21) produced little or no sign of shock. In MDP-primed mice, SiK213 caused lethal shock, while ScT21 only had a weak effect. SiK213 induced decreases in blood platelets and 5-hydroxytryptamine (5HT) preceding the shock, while the effects of ScT21 were weak. The SiK213-induced 5HT decrease and shock were reduced by a complement-C5 inhibitor. These results suggest that (i). streptococcal bacterial cells can induce rapid platelet responses, (ii). complement-dependent degradation of platelets may be involved in streptococcus-induced shock, (iii). the streptococcus-induced platelet degradation or degranulation may occur largely in the systemic circulation, and (iv). platelets may play a role not only in infectious diseases caused by gram-negative bacteria, but also in diseases caused by gram-positive bacteria." @default.
- W1990991109 created "2016-06-24" @default.
- W1990991109 creator A5005067510 @default.
- W1990991109 creator A5027506482 @default.
- W1990991109 creator A5032457888 @default.
- W1990991109 creator A5052122814 @default.
- W1990991109 creator A5066577467 @default.
- W1990991109 creator A5080517915 @default.
- W1990991109 date "2003-12-16" @default.
- W1990991109 modified "2023-10-10" @default.
- W1990991109 title "Platelet responses and anaphylaxis-like shock induced in mice by intravenous injection of whole cells of oral streptococci" @default.
- W1990991109 cites W1496746250 @default.
- W1990991109 cites W1861083212 @default.
- W1990991109 cites W1898962613 @default.
- W1990991109 cites W1965225268 @default.
- W1990991109 cites W1992400163 @default.
- W1990991109 cites W1997870290 @default.
- W1990991109 cites W1998855088 @default.
- W1990991109 cites W2003432589 @default.
- W1990991109 cites W2042207100 @default.
- W1990991109 cites W2049284457 @default.
- W1990991109 cites W2049351087 @default.
- W1990991109 cites W2060712084 @default.
- W1990991109 cites W2072962970 @default.
- W1990991109 cites W2085526527 @default.
- W1990991109 cites W2099479741 @default.
- W1990991109 cites W2114361126 @default.
- W1990991109 cites W2117496725 @default.
- W1990991109 cites W2158861974 @default.
- W1990991109 cites W341753937 @default.
- W1990991109 doi "https://doi.org/10.1046/j.0902-0055.2002.00107.x" @default.
- W1990991109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14678471" @default.
- W1990991109 hasPublicationYear "2003" @default.
- W1990991109 type Work @default.
- W1990991109 sameAs 1990991109 @default.
- W1990991109 citedByCount "15" @default.
- W1990991109 countsByYear W19909911092012 @default.
- W1990991109 countsByYear W19909911092013 @default.
- W1990991109 countsByYear W19909911092014 @default.
- W1990991109 countsByYear W19909911092016 @default.
- W1990991109 countsByYear W19909911092019 @default.
- W1990991109 crossrefType "journal-article" @default.
- W1990991109 hasAuthorship W1990991109A5005067510 @default.
- W1990991109 hasAuthorship W1990991109A5027506482 @default.
- W1990991109 hasAuthorship W1990991109A5032457888 @default.
- W1990991109 hasAuthorship W1990991109A5052122814 @default.
- W1990991109 hasAuthorship W1990991109A5066577467 @default.
- W1990991109 hasAuthorship W1990991109A5080517915 @default.
- W1990991109 hasConcept C126322002 @default.
- W1990991109 hasConcept C170493617 @default.
- W1990991109 hasConcept C203014093 @default.
- W1990991109 hasConcept C2778276568 @default.
- W1990991109 hasConcept C2778663903 @default.
- W1990991109 hasConcept C2781300812 @default.
- W1990991109 hasConcept C49802076 @default.
- W1990991109 hasConcept C501593827 @default.
- W1990991109 hasConcept C523546767 @default.
- W1990991109 hasConcept C54355233 @default.
- W1990991109 hasConcept C55493867 @default.
- W1990991109 hasConcept C71924100 @default.
- W1990991109 hasConcept C86803240 @default.
- W1990991109 hasConcept C89423630 @default.
- W1990991109 hasConcept C89560881 @default.
- W1990991109 hasConceptScore W1990991109C126322002 @default.
- W1990991109 hasConceptScore W1990991109C170493617 @default.
- W1990991109 hasConceptScore W1990991109C203014093 @default.
- W1990991109 hasConceptScore W1990991109C2778276568 @default.
- W1990991109 hasConceptScore W1990991109C2778663903 @default.
- W1990991109 hasConceptScore W1990991109C2781300812 @default.
- W1990991109 hasConceptScore W1990991109C49802076 @default.
- W1990991109 hasConceptScore W1990991109C501593827 @default.
- W1990991109 hasConceptScore W1990991109C523546767 @default.
- W1990991109 hasConceptScore W1990991109C54355233 @default.
- W1990991109 hasConceptScore W1990991109C55493867 @default.
- W1990991109 hasConceptScore W1990991109C71924100 @default.
- W1990991109 hasConceptScore W1990991109C86803240 @default.
- W1990991109 hasConceptScore W1990991109C89423630 @default.
- W1990991109 hasConceptScore W1990991109C89560881 @default.
- W1990991109 hasIssue "1" @default.
- W1990991109 hasLocation W19909911091 @default.
- W1990991109 hasLocation W19909911092 @default.
- W1990991109 hasOpenAccess W1990991109 @default.
- W1990991109 hasPrimaryLocation W19909911091 @default.
- W1990991109 hasRelatedWork W1780804146 @default.
- W1990991109 hasRelatedWork W1919661867 @default.
- W1990991109 hasRelatedWork W1992067487 @default.
- W1990991109 hasRelatedWork W2085998013 @default.
- W1990991109 hasRelatedWork W2136877262 @default.
- W1990991109 hasRelatedWork W2155428664 @default.
- W1990991109 hasRelatedWork W2317212064 @default.
- W1990991109 hasRelatedWork W2469514760 @default.
- W1990991109 hasRelatedWork W3099247907 @default.
- W1990991109 hasRelatedWork W4256594047 @default.
- W1990991109 hasVolume "19" @default.
- W1990991109 isParatext "false" @default.
- W1990991109 isRetracted "false" @default.
- W1990991109 magId "1990991109" @default.
- W1990991109 workType "article" @default.