FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990994039> ?p ?o ?g. }

• W1990994039 endingPage "127" @default.
• W1990994039 startingPage "111" @default.
• W1990994039 abstract "SUMMARY Three replicative forms of RNA (RF I, RF II, and RF III) have been isolated from BHK cells infected with Semliki Forest virus. Using analytical and rate-zonal sedimentation the mol. wt. of these replicative forms were estimated to be 8.5 × 106, 5.5 × 106 and 3.1 × 106 respectively. After continuous labelling from 1 to 6 h post-infection, RF I constituted more than 80% of the total replicative forms. Competition hybridization experiments showed that one strand of RF I was 42S RNA which had opposite (negative) polarity to that found in the virus particle. The positive strand of RF I was 42S RNA. The negative strand of replicative intermediate (RI) was also found to be 42S RNA. No evidence was found for an RI with a 26S negative strand. RF I was shown to contain non-hydrogen bounded poly A at or near the 3′ end of the component 42S positive strand. Isolation and analysis of the poly A tract from RF I on an acrylamide gel showed it to be of essentially the same average size as the poly A tract from virus particle RNA. About 30% of the RI molecules contained non-hydrogen bonded poly A. No poly U was detected in either RF I or RI. The kinetics of positive and negative strand synthesis were investigated during virus multiplication. These experiments showed that the rate of negative strand synthesis reaches a maximum 2½ h post-infection and thereafter rapidly falls. The rate of positive strand synthesis increases rapidly up to 3 h post-infection and then remains constant for a further 3 to 4 h." @default.
• W1990994039 created "2016-06-24" @default.
• W1990994039 creator A5002717925 @default.
• W1990994039 creator A5039791331 @default.
• W1990994039 date "1975-07-01" @default.
• W1990994039 modified "2023-09-26" @default.
• W1990994039 title "Semliki Forest Virus Intracellular RNA: Properties of the Multi-stranded RNA Species and Kinetics of Positive and Negative Strand Synthesis" @default.
• W1990994039 cites W1487555429 @default.
• W1990994039 cites W1565982795 @default.
• W1990994039 cites W1590328304 @default.
• W1990994039 cites W1591012326 @default.
• W1990994039 cites W1736054616 @default.
• W1990994039 cites W1776957880 @default.
• W1990994039 cites W1825177814 @default.
• W1990994039 cites W1834344492 @default.
• W1990994039 cites W1855023888 @default.
• W1990994039 cites W1912408357 @default.
• W1990994039 cites W1964487430 @default.
• W1990994039 cites W1980260148 @default.
• W1990994039 cites W1992566484 @default.
• W1990994039 cites W2005389848 @default.
• W1990994039 cites W2010008787 @default.
• W1990994039 cites W2010518576 @default.
• W1990994039 cites W2011820868 @default.
• W1990994039 cites W2017205606 @default.
• W1990994039 cites W2021236961 @default.
• W1990994039 cites W2021914449 @default.
• W1990994039 cites W2023273413 @default.
• W1990994039 cites W2056997173 @default.
• W1990994039 cites W2059581344 @default.
• W1990994039 cites W2060725133 @default.
• W1990994039 cites W2063531051 @default.
• W1990994039 cites W2063948613 @default.
• W1990994039 cites W2068596126 @default.
• W1990994039 cites W2086172280 @default.
• W1990994039 cites W2086632936 @default.
• W1990994039 cites W2096598159 @default.
• W1990994039 cites W2105091208 @default.
• W1990994039 cites W2107995762 @default.
• W1990994039 cites W2154206275 @default.
• W1990994039 cites W2159181164 @default.
• W1990994039 cites W2163092880 @default.
• W1990994039 cites W2240726600 @default.
• W1990994039 cites W2408823084 @default.
• W1990994039 doi "https://doi.org/10.1099/0022-1317-28-1-111" @default.
• W1990994039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1159408" @default.
• W1990994039 hasPublicationYear "1975" @default.
• W1990994039 type Work @default.
• W1990994039 sameAs 1990994039 @default.
• W1990994039 citedByCount "46" @default.
• W1990994039 countsByYear W19909940392013 @default.
• W1990994039 countsByYear W19909940392014 @default.
• W1990994039 countsByYear W19909940392018 @default.
• W1990994039 countsByYear W19909940392021 @default.
• W1990994039 crossrefType "journal-article" @default.
• W1990994039 hasAuthorship W1990994039A5002717925 @default.
• W1990994039 hasAuthorship W1990994039A5039791331 @default.
• W1990994039 hasBestOaLocation W19909940391 @default.
• W1990994039 hasConcept C104317684 @default.
• W1990994039 hasConcept C12554922 @default.
• W1990994039 hasConcept C153911025 @default.
• W1990994039 hasConcept C159047783 @default.
• W1990994039 hasConcept C2522874641 @default.
• W1990994039 hasConcept C2780963514 @default.
• W1990994039 hasConcept C55493867 @default.
• W1990994039 hasConcept C67705224 @default.
• W1990994039 hasConcept C86803240 @default.
• W1990994039 hasConceptScore W1990994039C104317684 @default.
• W1990994039 hasConceptScore W1990994039C12554922 @default.
• W1990994039 hasConceptScore W1990994039C153911025 @default.
• W1990994039 hasConceptScore W1990994039C159047783 @default.
• W1990994039 hasConceptScore W1990994039C2522874641 @default.
• W1990994039 hasConceptScore W1990994039C2780963514 @default.
• W1990994039 hasConceptScore W1990994039C55493867 @default.
• W1990994039 hasConceptScore W1990994039C67705224 @default.
• W1990994039 hasConceptScore W1990994039C86803240 @default.
• W1990994039 hasIssue "1" @default.
• W1990994039 hasLocation W19909940391 @default.
• W1990994039 hasLocation W19909940392 @default.
• W1990994039 hasOpenAccess W1990994039 @default.
• W1990994039 hasPrimaryLocation W19909940391 @default.
• W1990994039 hasRelatedWork W1670049400 @default.
• W1990994039 hasRelatedWork W1763247189 @default.
• W1990994039 hasRelatedWork W1838492020 @default.
• W1990994039 hasRelatedWork W1976227661 @default.
• W1990994039 hasRelatedWork W2051646092 @default.
• W1990994039 hasRelatedWork W2119589621 @default.
• W1990994039 hasRelatedWork W2139087689 @default.
• W1990994039 hasRelatedWork W2152359360 @default.
• W1990994039 hasRelatedWork W2314173690 @default.
• W1990994039 hasRelatedWork W2989604007 @default.
• W1990994039 hasVolume "28" @default.
• W1990994039 isParatext "false" @default.
• W1990994039 isRetracted "false" @default.
• W1990994039 magId "1990994039" @default.
• W1990994039 workType "article" @default.