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- W1990995217 abstract "Gold thiomalate (40 μM), penicillamine (40 μM), and histidine (20 μM) inhibit the copper-catalyzed (20 μM) thermal aggregation of human gamma globulin (0.8 mg/ml). At these concentrations, inhibition of gamma globulin aggregation was 87%, 96%, and 99% complete. This effect may be related to the reported suppressive effect of these agents in rheumatoid arthritis and adds support to the hypothesis that the hypohistidinemia of rheumatoid arthritis participates in the pathogenesis of the disease." @default.
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- W1990995217 date "1974-01-01" @default.
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- W1990995217 title "Copper-catalyzed thermal aggregation of human gamma-globulin inhibition by histidine, gold thiomalate, and penicillamine" @default.
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- W1990995217 doi "https://doi.org/10.1002/art.1780170113" @default.
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