Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991008573> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1991008573 endingPage "216" @default.
- W1991008573 startingPage "213" @default.
- W1991008573 abstract "Esophageal cancer ranks 8th among the most frequently occurring cancers of the world. The exact cause of esophageal squamous cell carcinoma (ESCC) is unknown; however, some factors like smoking, alcohol intake, consumption of fungal-contaminated, spicy, or nitrosamine-containing foodstuffs and hot beverages, together with various genetic factors, have been found associated with the occurrence of this disease in various parts of the world. Much work has been carried out to elucidate the role of various gene mutations and polymorphisms in esophageal mucosal cancer. Previous studies have suggested that esophageal cancer-related gene 1 (<i>ECRG1</i>), as a novel candidate of the tumor suppressor gene family, is expressed in normal esophagus, liver, colon and lung tissues, but the expression is seen to be down-regulated in tumors, especially in ESCC, and in adjacent tissues. The Arg290Gln polymorphism in exon 8 of the <i>ECRG1 </i>gene has been studied in particular in a number of cases and has been observed to play an active role in the development of ESCC. This suggests that substitution of the arginine in the conserved catalytic domain of the ECRG1 protein might reduce its catalytic capacity by impacting its 3-dimensional conformation, thereby causing the genetic susceptibility to ESCC." @default.
- W1991008573 created "2016-06-24" @default.
- W1991008573 creator A5038235830 @default.
- W1991008573 creator A5047397949 @default.
- W1991008573 creator A5064747207 @default.
- W1991008573 creator A5074130748 @default.
- W1991008573 date "2013-01-01" @default.
- W1991008573 modified "2023-10-17" @default.
- W1991008573 title "<b><i>ECRG1</i></b> and Its Relationship with Esophageal Cancer: A Brief Review" @default.
- W1991008573 cites W1607367030 @default.
- W1991008573 cites W1969153822 @default.
- W1991008573 cites W1978237191 @default.
- W1991008573 cites W1993188029 @default.
- W1991008573 cites W2004091546 @default.
- W1991008573 cites W2020830322 @default.
- W1991008573 cites W2025092054 @default.
- W1991008573 cites W2026726511 @default.
- W1991008573 cites W2031726037 @default.
- W1991008573 cites W2104286553 @default.
- W1991008573 cites W2110752622 @default.
- W1991008573 cites W2111690889 @default.
- W1991008573 cites W2126750801 @default.
- W1991008573 doi "https://doi.org/10.1159/000349960" @default.
- W1991008573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23548972" @default.
- W1991008573 hasPublicationYear "2013" @default.
- W1991008573 type Work @default.
- W1991008573 sameAs 1991008573 @default.
- W1991008573 citedByCount "7" @default.
- W1991008573 countsByYear W19910085732013 @default.
- W1991008573 countsByYear W19910085732014 @default.
- W1991008573 countsByYear W19910085732015 @default.
- W1991008573 countsByYear W19910085732017 @default.
- W1991008573 countsByYear W19910085732020 @default.
- W1991008573 countsByYear W19910085732021 @default.
- W1991008573 crossrefType "journal-article" @default.
- W1991008573 hasAuthorship W1991008573A5038235830 @default.
- W1991008573 hasAuthorship W1991008573A5047397949 @default.
- W1991008573 hasAuthorship W1991008573A5064747207 @default.
- W1991008573 hasAuthorship W1991008573A5074130748 @default.
- W1991008573 hasConcept C104317684 @default.
- W1991008573 hasConcept C121608353 @default.
- W1991008573 hasConcept C126322002 @default.
- W1991008573 hasConcept C2776256026 @default.
- W1991008573 hasConcept C2777819096 @default.
- W1991008573 hasConcept C2779742542 @default.
- W1991008573 hasConcept C2994415158 @default.
- W1991008573 hasConcept C36823959 @default.
- W1991008573 hasConcept C502942594 @default.
- W1991008573 hasConcept C54355233 @default.
- W1991008573 hasConcept C71924100 @default.
- W1991008573 hasConcept C86803240 @default.
- W1991008573 hasConceptScore W1991008573C104317684 @default.
- W1991008573 hasConceptScore W1991008573C121608353 @default.
- W1991008573 hasConceptScore W1991008573C126322002 @default.
- W1991008573 hasConceptScore W1991008573C2776256026 @default.
- W1991008573 hasConceptScore W1991008573C2777819096 @default.
- W1991008573 hasConceptScore W1991008573C2779742542 @default.
- W1991008573 hasConceptScore W1991008573C2994415158 @default.
- W1991008573 hasConceptScore W1991008573C36823959 @default.
- W1991008573 hasConceptScore W1991008573C502942594 @default.
- W1991008573 hasConceptScore W1991008573C54355233 @default.
- W1991008573 hasConceptScore W1991008573C71924100 @default.
- W1991008573 hasConceptScore W1991008573C86803240 @default.
- W1991008573 hasIssue "4" @default.
- W1991008573 hasLocation W19910085731 @default.
- W1991008573 hasLocation W19910085732 @default.
- W1991008573 hasOpenAccess W1991008573 @default.
- W1991008573 hasPrimaryLocation W19910085731 @default.
- W1991008573 hasRelatedWork W1968861569 @default.
- W1991008573 hasRelatedWork W2093125411 @default.
- W1991008573 hasRelatedWork W2118812285 @default.
- W1991008573 hasRelatedWork W2352701899 @default.
- W1991008573 hasRelatedWork W2352780564 @default.
- W1991008573 hasRelatedWork W2406182809 @default.
- W1991008573 hasRelatedWork W2582733070 @default.
- W1991008573 hasRelatedWork W2951456844 @default.
- W1991008573 hasRelatedWork W70397127 @default.
- W1991008573 hasRelatedWork W890495913 @default.
- W1991008573 hasVolume "36" @default.
- W1991008573 isParatext "false" @default.
- W1991008573 isRetracted "false" @default.
- W1991008573 magId "1991008573" @default.
- W1991008573 workType "article" @default.