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- W1991023503 abstract "Retroviral vectors are used widely in research and are also being designed for use in gene therapy trials. In practice, these vectors usually contain a marker gene, which is often a drug selection gene. In this report, a novel retroviral vector has been constructed which contains a gene that allows selection for infected cells by a magnet. This gene is a single-chain antibody (sFv) to a specific hapten molecule 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (phOx). sFv specific for phOx is displayed on the surface of infected cells. This feature allows binding to phOx-BSA coated magnetic beads which are used to isolate the infected cells." @default.
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- W1991023503 date "2001-05-01" @default.
- W1991023503 modified "2023-09-26" @default.
- W1991023503 title "A novel retroviral vector that allows the magnetic selection of infected cells" @default.
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- W1991023503 doi "https://doi.org/10.1016/s0166-0934(00)00298-6" @default.
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