FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991052011> ?p ?o ?g. }

• W1991052011 endingPage "22" @default.
• W1991052011 startingPage "17" @default.
• W1991052011 abstract "Epidermal growth factor receptor (EGFR) mutations are more common in lung adenocarcinoma and in female patients of East-Asian origin. We aimed to assess the expression of female hormone receptors in East-Asian lung adenocarcinomas, their correlation with EGFR mutations, and prognostic significance.Estrogen receptor (ER)alpha, ERbeta, progesterone receptor (PR), and Her-2 expression were examined using immunohistochemical methods on 109 lung adenocarcinoma cases. EGFR mutations were analyzed by partially denaturing high performance liquid chromatography. Association of hormone receptor with clinical factors was assessed using the Fisher's exact test. Associations with survival were assessed using the Cox proportional hazard model.Using scoring criteria routinely used for breast cancer, there were four (4%) ERalpha, one (1%) ERbeta, six (6%) PR, and one (1%) Her-2 positive cases. Considering any staining as positive, 14 (14%) ERalpha, 10 (9%) ERbeta, 12 (12%) PR, and 26 (24%) Her-2 cases were positive. Thirty-nine patients (39%) had EGFR mutations. ERalpha positivity was significantly associated with ERbeta and PR positivity. There were more EGFR mutations seen in tumors with ERbeta positivity (60%) compared with those with negative expression (37.9%), and there was a trend toward a poorer outcome for patients with tumor that were positive for ERbeta and Her-2.We found that ERalpha, ERbeta, PR, and Her-2 expression in lung adenocarcinoma are present but limited. This suggests that hormonal influence may not be an important factor to account for the high prevalence of lung cancer among the East-Asian women." @default.
• W1991052011 created "2016-06-24" @default.
• W1991052011 creator A5007311021 @default.
• W1991052011 creator A5027621525 @default.
• W1991052011 creator A5034799187 @default.
• W1991052011 creator A5035273217 @default.
• W1991052011 creator A5040753767 @default.
• W1991052011 creator A5052071706 @default.
• W1991052011 creator A5070755871 @default.
• W1991052011 creator A5073819873 @default.
• W1991052011 creator A5091787274 @default.
• W1991052011 date "2010-01-01" @default.
• W1991052011 modified "2023-10-16" @default.
• W1991052011 title "Correlation between Epidermal Growth Factor Receptor Mutations and Expression of Female Hormone Receptors in East-Asian Lung Adenocarcinomas" @default.
• W1991052011 cites W1845740087 @default.
• W1991052011 cites W1908715206 @default.
• W1991052011 cites W1966780564 @default.
• W1991052011 cites W1969658446 @default.
• W1991052011 cites W1978617280 @default.
• W1991052011 cites W1979245812 @default.
• W1991052011 cites W1991378725 @default.
• W1991052011 cites W2001065504 @default.
• W1991052011 cites W2008866655 @default.
• W1991052011 cites W2012375478 @default.
• W1991052011 cites W2034877524 @default.
• W1991052011 cites W2051431808 @default.
• W1991052011 cites W2064448731 @default.
• W1991052011 cites W2071013205 @default.
• W1991052011 cites W2074961178 @default.
• W1991052011 cites W2076878057 @default.
• W1991052011 cites W2081725472 @default.
• W1991052011 cites W2110841384 @default.
• W1991052011 cites W2132542518 @default.
• W1991052011 cites W2143859186 @default.
• W1991052011 cites W2148174696 @default.
• W1991052011 cites W2153631705 @default.
• W1991052011 cites W2163844751 @default.
• W1991052011 cites W2168440234 @default.
• W1991052011 doi "https://doi.org/10.1097/jto.0b013e3181c0a602" @default.
• W1991052011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19875972" @default.
• W1991052011 hasPublicationYear "2010" @default.
• W1991052011 type Work @default.
• W1991052011 sameAs 1991052011 @default.
• W1991052011 citedByCount "30" @default.
• W1991052011 countsByYear W19910520112012 @default.
• W1991052011 countsByYear W19910520112013 @default.
• W1991052011 countsByYear W19910520112015 @default.
• W1991052011 countsByYear W19910520112016 @default.
• W1991052011 countsByYear W19910520112017 @default.
• W1991052011 countsByYear W19910520112018 @default.
• W1991052011 countsByYear W19910520112019 @default.
• W1991052011 countsByYear W19910520112020 @default.
• W1991052011 countsByYear W19910520112021 @default.
• W1991052011 countsByYear W19910520112022 @default.
• W1991052011 countsByYear W19910520112023 @default.
• W1991052011 crossrefType "journal-article" @default.
• W1991052011 hasAuthorship W1991052011A5007311021 @default.
• W1991052011 hasAuthorship W1991052011A5027621525 @default.
• W1991052011 hasAuthorship W1991052011A5034799187 @default.
• W1991052011 hasAuthorship W1991052011A5035273217 @default.
• W1991052011 hasAuthorship W1991052011A5040753767 @default.
• W1991052011 hasAuthorship W1991052011A5052071706 @default.
• W1991052011 hasAuthorship W1991052011A5070755871 @default.
• W1991052011 hasAuthorship W1991052011A5073819873 @default.
• W1991052011 hasAuthorship W1991052011A5091787274 @default.
• W1991052011 hasBestOaLocation W19910520111 @default.
• W1991052011 hasConcept C121608353 @default.
• W1991052011 hasConcept C126322002 @default.
• W1991052011 hasConcept C142724271 @default.
• W1991052011 hasConcept C143998085 @default.
• W1991052011 hasConcept C170493617 @default.
• W1991052011 hasConcept C172313692 @default.
• W1991052011 hasConcept C204232928 @default.
• W1991052011 hasConcept C207103383 @default.
• W1991052011 hasConcept C23589133 @default.
• W1991052011 hasConcept C2776256026 @default.
• W1991052011 hasConcept C2777164284 @default.
• W1991052011 hasConcept C2777714996 @default.
• W1991052011 hasConcept C2779438470 @default.
• W1991052011 hasConcept C2781182431 @default.
• W1991052011 hasConcept C44249647 @default.
• W1991052011 hasConcept C502942594 @default.
• W1991052011 hasConcept C530470458 @default.
• W1991052011 hasConcept C71924100 @default.
• W1991052011 hasConcept C84606932 @default.
• W1991052011 hasConcept C96307122 @default.
• W1991052011 hasConcept C98717036 @default.
• W1991052011 hasConceptScore W1991052011C121608353 @default.
• W1991052011 hasConceptScore W1991052011C126322002 @default.
• W1991052011 hasConceptScore W1991052011C142724271 @default.
• W1991052011 hasConceptScore W1991052011C143998085 @default.
• W1991052011 hasConceptScore W1991052011C170493617 @default.
• W1991052011 hasConceptScore W1991052011C172313692 @default.
• W1991052011 hasConceptScore W1991052011C204232928 @default.
• W1991052011 hasConceptScore W1991052011C207103383 @default.
• W1991052011 hasConceptScore W1991052011C23589133 @default.
• W1991052011 hasConceptScore W1991052011C2776256026 @default.
• W1991052011 hasConceptScore W1991052011C2777164284 @default.

• next