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- W1991098086 abstract "Rat liver microsomes catalyze NADPH-dependent irreversible binding of metabolites of DOPA and DOPAmine to microsomal protein and to BSA. Binding is inhibited by cysteine and the singlet oxygen quencher 1,4-diaza-bicyclo(2.2.2)octane. Irreversible binding to BSA is also catalyzed by mushroom tyrosinase, xanthine oxidase, and NADPH-cytochrome c reductase. The results suggest that in the microsomal system the participation of the hemoprotein, cytochrome P-450, is not an absolute requirement for the irreversible binding of metabolites of DOPA and DOPAmine to proteins." @default.
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- W1991098086 date "1975-10-01" @default.
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- W1991098086 title "Irreversible binding of dopa and dopamine metabolites to protein by rat liver microsomes" @default.
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- W1991098086 doi "https://doi.org/10.1016/0006-291x(75)90514-8" @default.
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