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- W1991101851 abstract "Chemosterilant activity in the house fly, Musca domestica L., cytotoxicity to mouse fibroblast cells grown in tissue culture, and acute oral toxicity in mice were determined for a series of P-N ring chemicals related to apholate. There was a positive correlation between percent ethylene imine in the molecule, water solubility, and degree of insect sterility. Substituents on the P-N ring also had a marked influence on sterilant activity. Mammalian toxicity was related to percent aziridine on the ring and the type of substituent. The cell toxicity test was not sufficiently selective for highly active insect sterilants; nevertheless none of the active insect sterilants were missed by this method." @default.
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- W1991101851 date "1965-10-01" @default.
- W1991101851 modified "2023-10-17" @default.
- W1991101851 title "Chemosterilant Properties, Cytotoxicity, and Mammalian Toxicity of Apholate and Other P-N Ring Chemicals" @default.
- W1991101851 doi "https://doi.org/10.1093/jee/58.5.929" @default.
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