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- W1991108520 abstract "Furacin (nitrofurazone) has been used for the treatment of metastatic testicular carcinoma because of the disintegration of seminiferous epithelium produced in animals by nitrofurans. 1 Although a beneficial effect on the malignancy has occurred, a severe polyneuropathy has usually developed. Wildermuth's patient, who had received 49 gm. of Furacin during a 4-week period, developed a severe, painful peripheral neuropathy. The neuropathy improved slightly in 3 weeks after the medication was stopped, but one week after medication was resumed, he was hospitalized because of unbearable pain in the extremities requiring narcotics and nerve blocks for one month. 2 The patient reported by Politano developed a severe peripheral neuritis after receiving 28 gm. of Furacin in an 18-day period. 3 A patient reported by Szczukowski developed a severe peripheral neuritis after receiving 34 gm. of Furacin orally during a 45-day period. The symptoms persisted for 21/2 months and required heavy doses of" @default.
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- W1991108520 date "1960-12-01" @default.
- W1991108520 modified "2023-09-23" @default.
- W1991108520 title "Polyneuropathy Associated with Nitrofuran Therapy" @default.
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- W1991108520 doi "https://doi.org/10.1001/archneur.1960.00450060044004" @default.
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