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- W1991134900 abstract "Male, but not female, rat liver cytosol contains an estrogen-binding protein with unique properties: rapid binding of estradiol, high binding capacity, moderate affinity for estradiol, and specificity for steroidal estrogens and weak androgens, but not for nonsteroidal estrogens or other steroids. The estradiol-binding activity of this protein is reduced in cytosol from livers of alcohol-fed rats as compared to that from their isocalorically fed controls. The properties of this male-specific hepatic estrogen-binding protein suggest a role for this protein in the regulation of estrogen levels in the male animal. Moreover, the reduction in activity of this unique protein in the liver of alcohol-fed animals may explain, at least in part, the feminization commonly seen in chronic alcoholic men." @default.
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- W1991134900 date "1981-03-01" @default.
- W1991134900 modified "2023-09-25" @default.
- W1991134900 title "Effect of Ethanol Feeding upon Levels of a Male-Specific Hepatic Estrogen-Binding Protein: A Possible Mechanism for Feminization" @default.
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- W1991134900 doi "https://doi.org/10.1111/j.1530-0277.1981.tb04885.x" @default.
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