FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991168871> ?p ?o ?g. }

• W1991168871 endingPage "28" @default.
• W1991168871 startingPage "21" @default.
• W1991168871 abstract "Timeless was originally identified in Drosophila as an essential component of circadian cycle regulation. In mammals, the ortholog of Timeless (Tim) has also implicated in cell cycle control and embryonic development. In this study, we generated a specific antibody against Tim, and carried out expression and localization analyses of Tim during mouse brain development. In Western blotting, Tim was detected throughout the developmental stage. In immunohistochemical analyses, Tim was detected strongly in neurons in the ventricular zone/subventricular zone and moderately in cortical neurons during corticogenesis. In adult mouse brain, Tim was observed moderately in cortical neurons. Notably, Tim was enriched in the nucleus of cortical neurons from embryonic to early postnatal stages while it was distributed in the cytoplasm in the adult stage. Similar distribution change from nucleus to cytoplasm was observed in the hippocampal neurons between P0 and P30. In situ hybridization revealed that the tissue expression profile of Tim-mRNA was similar to that of the protein. In differentiated primary cultured mouse hippocampal neurons, Tim was detected in cell body, axon and dendrites. The obtained results suggest that Tim is expressed in neuronal tissues in a spatiotemporally regulated manner and involved in developmental stage-specific neuronal functions." @default.
• W1991168871 created "2016-06-24" @default.
• W1991168871 creator A5011609370 @default.
• W1991168871 creator A5015424874 @default.
• W1991168871 creator A5018558385 @default.
• W1991168871 creator A5041999667 @default.
• W1991168871 creator A5043634159 @default.
• W1991168871 creator A5048500772 @default.
• W1991168871 creator A5078293163 @default.
• W1991168871 creator A5091536972 @default.
• W1991168871 date "2015-03-01" @default.
• W1991168871 modified "2023-09-25" @default.
• W1991168871 title "Morphological characterization of mammalian Timeless in the mouse brain development" @default.
• W1991168871 cites W1512634144 @default.
• W1991168871 cites W1514624682 @default.
• W1991168871 cites W1519382622 @default.
• W1991168871 cites W1567975066 @default.
• W1991168871 cites W1991476151 @default.
• W1991168871 cites W1997746998 @default.
• W1991168871 cites W2004287746 @default.
• W1991168871 cites W2006907150 @default.
• W1991168871 cites W2008934254 @default.
• W1991168871 cites W2013370526 @default.
• W1991168871 cites W2025285508 @default.
• W1991168871 cites W2033026766 @default.
• W1991168871 cites W2040876904 @default.
• W1991168871 cites W2044342230 @default.
• W1991168871 cites W2049525029 @default.
• W1991168871 cites W2061305437 @default.
• W1991168871 cites W2085109991 @default.
• W1991168871 cites W2085510292 @default.
• W1991168871 cites W2120055448 @default.
• W1991168871 cites W2164585152 @default.
• W1991168871 doi "https://doi.org/10.1016/j.neures.2014.10.017" @default.
• W1991168871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25448545" @default.
• W1991168871 hasPublicationYear "2015" @default.
• W1991168871 type Work @default.
• W1991168871 sameAs 1991168871 @default.
• W1991168871 citedByCount "7" @default.
• W1991168871 countsByYear W19911688712015 @default.
• W1991168871 countsByYear W19911688712016 @default.
• W1991168871 countsByYear W19911688712019 @default.
• W1991168871 countsByYear W19911688712021 @default.
• W1991168871 countsByYear W19911688712023 @default.
• W1991168871 crossrefType "journal-article" @default.
• W1991168871 hasAuthorship W1991168871A5011609370 @default.
• W1991168871 hasAuthorship W1991168871A5015424874 @default.
• W1991168871 hasAuthorship W1991168871A5018558385 @default.
• W1991168871 hasAuthorship W1991168871A5041999667 @default.
• W1991168871 hasAuthorship W1991168871A5043634159 @default.
• W1991168871 hasAuthorship W1991168871A5048500772 @default.
• W1991168871 hasAuthorship W1991168871A5078293163 @default.
• W1991168871 hasAuthorship W1991168871A5091536972 @default.
• W1991168871 hasConcept C104317684 @default.
• W1991168871 hasConcept C105580179 @default.
• W1991168871 hasConcept C108619961 @default.
• W1991168871 hasConcept C113246987 @default.
• W1991168871 hasConcept C121446783 @default.
• W1991168871 hasConcept C136834591 @default.
• W1991168871 hasConcept C145103041 @default.
• W1991168871 hasConcept C148762608 @default.
• W1991168871 hasConcept C169760540 @default.
• W1991168871 hasConcept C190062978 @default.
• W1991168871 hasConcept C201750760 @default.
• W1991168871 hasConcept C202751555 @default.
• W1991168871 hasConcept C2777542384 @default.
• W1991168871 hasConcept C2778880379 @default.
• W1991168871 hasConcept C2780723820 @default.
• W1991168871 hasConcept C28328180 @default.
• W1991168871 hasConcept C4746552 @default.
• W1991168871 hasConcept C54355233 @default.
• W1991168871 hasConcept C81439078 @default.
• W1991168871 hasConcept C86803240 @default.
• W1991168871 hasConcept C95444343 @default.
• W1991168871 hasConceptScore W1991168871C104317684 @default.
• W1991168871 hasConceptScore W1991168871C105580179 @default.
• W1991168871 hasConceptScore W1991168871C108619961 @default.
• W1991168871 hasConceptScore W1991168871C113246987 @default.
• W1991168871 hasConceptScore W1991168871C121446783 @default.
• W1991168871 hasConceptScore W1991168871C136834591 @default.
• W1991168871 hasConceptScore W1991168871C145103041 @default.
• W1991168871 hasConceptScore W1991168871C148762608 @default.
• W1991168871 hasConceptScore W1991168871C169760540 @default.
• W1991168871 hasConceptScore W1991168871C190062978 @default.
• W1991168871 hasConceptScore W1991168871C201750760 @default.
• W1991168871 hasConceptScore W1991168871C202751555 @default.
• W1991168871 hasConceptScore W1991168871C2777542384 @default.
• W1991168871 hasConceptScore W1991168871C2778880379 @default.
• W1991168871 hasConceptScore W1991168871C2780723820 @default.
• W1991168871 hasConceptScore W1991168871C28328180 @default.
• W1991168871 hasConceptScore W1991168871C4746552 @default.
• W1991168871 hasConceptScore W1991168871C54355233 @default.
• W1991168871 hasConceptScore W1991168871C81439078 @default.
• W1991168871 hasConceptScore W1991168871C86803240 @default.
• W1991168871 hasConceptScore W1991168871C95444343 @default.
• W1991168871 hasFunder F4320309807 @default.
• W1991168871 hasFunder F4320320912 @default.
• W1991168871 hasFunder F4320327252 @default.

• next