Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991177887> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1991177887 endingPage "256" @default.
- W1991177887 startingPage "253" @default.
- W1991177887 abstract "The effects of selective phosphodiesterase isozyme inhibitors on eosinophil infiltration induced by antigen challenge or by exposure to an aerosol of platelet-activating factor (PAF) were investigated in the guinea-pig. Pretreatment 24 h and 3 h before antigen challenge or PAF exposure with theophylline (100 mg/kg), rolipram (5 mg/kg) and Ro 20-1724 (30 mg/kg) significantly reduced the increase in eosinophil numbers in bronchoalveolar lavage fluid. In contrast, milrinone, SK&F 94-120 and zaprinast were ineffective against antigen-induced eosinophil recruitment. Theophylline, rolipram and Ro 20-1724 also significantly reduced the release of eosinophil peroxidase into the bronchoalveolar lavage fluid. It is suggested that inhibitors of type IV phosphodiesterase have anti-inflammatory effects in the airways and may be useful in the treatment of asthma." @default.
- W1991177887 created "2016-06-24" @default.
- W1991177887 creator A5017818925 @default.
- W1991177887 creator A5019551120 @default.
- W1991177887 creator A5043484641 @default.
- W1991177887 creator A5045325079 @default.
- W1991177887 creator A5072778963 @default.
- W1991177887 date "1994-04-01" @default.
- W1991177887 modified "2023-10-18" @default.
- W1991177887 title "Effects of isozyme-selective phosphodiesterase inhibitors on eosinophil infiltration in the guinea-pig lung" @default.
- W1991177887 cites W1978639888 @default.
- W1991177887 cites W1990293385 @default.
- W1991177887 cites W2006920347 @default.
- W1991177887 cites W2037663265 @default.
- W1991177887 cites W2071331983 @default.
- W1991177887 cites W2158101364 @default.
- W1991177887 cites W2164508592 @default.
- W1991177887 doi "https://doi.org/10.1016/0014-2999(94)90107-4" @default.
- W1991177887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8026552" @default.
- W1991177887 hasPublicationYear "1994" @default.
- W1991177887 type Work @default.
- W1991177887 sameAs 1991177887 @default.
- W1991177887 citedByCount "51" @default.
- W1991177887 countsByYear W19911778872012 @default.
- W1991177887 crossrefType "journal-article" @default.
- W1991177887 hasAuthorship W1991177887A5017818925 @default.
- W1991177887 hasAuthorship W1991177887A5019551120 @default.
- W1991177887 hasAuthorship W1991177887A5043484641 @default.
- W1991177887 hasAuthorship W1991177887A5045325079 @default.
- W1991177887 hasAuthorship W1991177887A5072778963 @default.
- W1991177887 hasConcept C126322002 @default.
- W1991177887 hasConcept C134018914 @default.
- W1991177887 hasConcept C155710745 @default.
- W1991177887 hasConcept C181199279 @default.
- W1991177887 hasConcept C185592680 @default.
- W1991177887 hasConcept C203014093 @default.
- W1991177887 hasConcept C2776042228 @default.
- W1991177887 hasConcept C2776645727 @default.
- W1991177887 hasConcept C2776766087 @default.
- W1991177887 hasConcept C2776846068 @default.
- W1991177887 hasConcept C2776958096 @default.
- W1991177887 hasConcept C2777037409 @default.
- W1991177887 hasConcept C2777714996 @default.
- W1991177887 hasConcept C2777961210 @default.
- W1991177887 hasConcept C2778081958 @default.
- W1991177887 hasConcept C2778095195 @default.
- W1991177887 hasConcept C2778815084 @default.
- W1991177887 hasConcept C55493867 @default.
- W1991177887 hasConcept C62826618 @default.
- W1991177887 hasConcept C71924100 @default.
- W1991177887 hasConcept C98274493 @default.
- W1991177887 hasConceptScore W1991177887C126322002 @default.
- W1991177887 hasConceptScore W1991177887C134018914 @default.
- W1991177887 hasConceptScore W1991177887C155710745 @default.
- W1991177887 hasConceptScore W1991177887C181199279 @default.
- W1991177887 hasConceptScore W1991177887C185592680 @default.
- W1991177887 hasConceptScore W1991177887C203014093 @default.
- W1991177887 hasConceptScore W1991177887C2776042228 @default.
- W1991177887 hasConceptScore W1991177887C2776645727 @default.
- W1991177887 hasConceptScore W1991177887C2776766087 @default.
- W1991177887 hasConceptScore W1991177887C2776846068 @default.
- W1991177887 hasConceptScore W1991177887C2776958096 @default.
- W1991177887 hasConceptScore W1991177887C2777037409 @default.
- W1991177887 hasConceptScore W1991177887C2777714996 @default.
- W1991177887 hasConceptScore W1991177887C2777961210 @default.
- W1991177887 hasConceptScore W1991177887C2778081958 @default.
- W1991177887 hasConceptScore W1991177887C2778095195 @default.
- W1991177887 hasConceptScore W1991177887C2778815084 @default.
- W1991177887 hasConceptScore W1991177887C55493867 @default.
- W1991177887 hasConceptScore W1991177887C62826618 @default.
- W1991177887 hasConceptScore W1991177887C71924100 @default.
- W1991177887 hasConceptScore W1991177887C98274493 @default.
- W1991177887 hasIssue "1-3" @default.
- W1991177887 hasLocation W19911778871 @default.
- W1991177887 hasLocation W19911778872 @default.
- W1991177887 hasOpenAccess W1991177887 @default.
- W1991177887 hasPrimaryLocation W19911778871 @default.
- W1991177887 hasRelatedWork W1966650769 @default.
- W1991177887 hasRelatedWork W1980209155 @default.
- W1991177887 hasRelatedWork W1991177887 @default.
- W1991177887 hasRelatedWork W1997638241 @default.
- W1991177887 hasRelatedWork W1997718249 @default.
- W1991177887 hasRelatedWork W2046921980 @default.
- W1991177887 hasRelatedWork W2054384088 @default.
- W1991177887 hasRelatedWork W2087509980 @default.
- W1991177887 hasRelatedWork W2136727047 @default.
- W1991177887 hasRelatedWork W4247427913 @default.
- W1991177887 hasVolume "255" @default.
- W1991177887 isParatext "false" @default.
- W1991177887 isRetracted "false" @default.
- W1991177887 magId "1991177887" @default.
- W1991177887 workType "article" @default.