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• W1991210070 abstract "In organisms that provision young between fertilization and birth, mothers and their developing embryos are expected to be in conflict over embryonic growth. In mammalian embryos, the expression of Insulin-like growth factor II (IGF2) plays a key role in maternal-fetal interactions and is thought to be a focus of maternal-fetal conflict. Recent studies have suggested that IGF2 is also a focus of maternal-fetal conflict in placental fish in the family Poeciliidae. However, whether the expression of IGF2 influences offspring size, the trait over which mothers and embryos are likely to be in conflict, has not been assessed in a poeciliid. We tested whether embryonic IGF2 expression varied among four populations of a placental poeciliid that display large and consistent differences in offspring size at birth. We found that IGF2 expression varied significantly among embryonic stages with expression being 50% higher in early stage embryos than late stage embryos. There were no significant differences among populations in IGF2 expression; small differences in expression between population pairs with different offspring sizes were comparable in magnitude to those between population pairs with the same offspring sizes. Our results indicate that variation in IGF2 transcript abundance does not contribute to differences in offspring size among H. formosa populations." @default.
• W1991210070 created "2016-06-24" @default.
• W1991210070 creator A5076174956 @default.
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• W1991210070 date "2012-09-19" @default.
• W1991210070 modified "2023-10-18" @default.
• W1991210070 title "Embryonic IGF2 Expression Is Not Associated with Offspring Size among Populations of a Placental Fish" @default.
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• W1991210070 doi "https://doi.org/10.1371/journal.pone.0045463" @default.
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